Organisation/Company CSIC Department Centro Nacional de Biotecnología (CNB-CSIC) Research Field Medical sciences » Health sciences Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 30 Sep 2026 - 14:00 (Africa/Abidjan) Country Spain Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

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Offer Description A pre-doctoral position is available in the Nuclear Receptor Signaling Laboratory at the Spanish National Centre for Biotechnology (CNB-CSIC), Madrid, Spain. Principal Investigator: Mercedes Ricote.

Our laboratory investigates how transcriptional and epigenetic mechanisms regulate metabolism and immune function, with a particular focus on nuclear receptors. Building on recent discoveries from our group (J Exp Med 2026, Nature 2023, Blood 2023, Nature Communications 2020), we are currently exploring how maternal-derived signals influence neonatal metabolic and immune development.

The PhD project will examine how maternal diet and environmental factors shape metabolic and immune programming during early life. We aim to understand how bioactive metabolites present in breast milk regulate transcriptional and epigenetic pathways controlling metabolism and immune homeostasis under physiological and disease conditions. controlling metabolism and immune homeostasis under physiological and disease conditions. The project combines mouse genetics, immunology, metabolism,



and systems biology approaches, including tissue-specific knockout mouse models, next-generation sequencing technologies (bulk RNA-seq, scRNA-seq, ChIP-seq, ATAC-seq), proteomics, metabolomics, and bioinformatics analyses.

Where to apply

E-mail

Requirements

Research Field Biological sciences Education Level Master Degree or equivalent

Skills/Qualifications

- - Bachelor's degree in Life Sciences, Biomedicine, Biotechnology, or related disciplines.

- Master's degree in Biomedicine, Biotechnology, Biochemistry, Molecular Biology, or a related field (completed or expected before the start of the PhD).

- Excellent academic record.

- Good command of written and spoken English.

- Strong motivation for biomedical research and an academic career.

- Scientific curiosity, independence, and ability to work collaboratively in a multidisciplinary environment.

- Previous experience in molecular biology techniques.

- Certification for animal experimentation (Functions B and C) is desirable.

- Experience in bioinformatics (R and/or Python) is advantageous. xugodme

The successful candidate will join a highly collaborative and internationally recognized research group within a Severo Ochoa Centre of Excellence, with access to state-of-the-art facilities and advanced technological platforms.

Languages ENGLISH Level Good

Research Field Medical sciences » Health sciencesBiological sciences » Biology

Additional Information

Additional comments

This contract will be funded by Comunidad de Madrid SALUD25 call ref. SAL-2025/SAL-GL-1193.

Work Location(s)

Number of offers available 1 Company/Institute Centro Nacional de Biotecnología (CNB-CSIC) Country Spain State/Province Madrid City Madrid Postal Code 28049 Street Darwin, 3 Geofield

📌 PhD student - Nuclear Receptor Signaling Laboratory @CNB-CSIC (España)
🏢 CSIC
📍 España