Compensation: Executive-level salary + meaningful equity participation

We are partnering with an ambitious, science-driven biotech based in Barcelona to appoint a Chief Scientific Officer who will define, lead, and own the company’s scientific strategy from discovery through early clinical development. This is a pivotal executive role for a senior scientific leader who combines deep technical credibility with strategic foresight and decisive leadership.

As CSO, you will be entrusted with shaping the long‑term scientific vision, translating cutting‑edge research into robust development programmes, and building a high‑performing scientific organisation capable of delivering value at pace.

Key Responsibilities

Set and own the scientific vision and R&D; strategy, aligned with corporate and investor objectives

Lead discovery, preclinical, and translational activities, ensuring scientific excellence and disciplined execution

Act as the scientific authority internally and externally, representing the company to investors, partners, and key opinion leaders

Build, mentor, and scale a world‑class scientific team, fostering a culture of accountability, innovation, and rigor

Drive decision-making across pipeline prioritisation, resource allocation, and risk management

Oversee scientific governance, data integrity,



and readiness for regulatory interactions

Partner closely with the CEO and Board to support fundraising, partnering, and long‑term growth strategy

Candidate Profile

PhD or MD/PhD in a relevant scientific discipline

Proven leadership experience at executive or senior R&D; leadership level within biotech or pharma

Strong track record of advancing programmes from discovery through IND‑enabling / early clinical stages

Demonstrated ability to operate in fast‑paced, capital‑efficient environments

Strategic thinker with the confidence to make high‑impact scientific and organisational decisions

Excellent communicator, capable of influencing at Board and investor level

Why Join

Opportunity to shape the scientific direction of a high‑potential biotech at a critical stage of growth

Significant ownership and influence at executive leadership level

Work from Barcelona — one of Europe’s leading life science hubs, offering exceptional quality of life

Competitive executive compensation with meaningful equity upside

Next Steps This role is being handled on a confidential basis. For an initial discussion, please apply or contact our retained search team directly.

Seniority level

Executive

Employment type

Full‑time

Job function

Research

📌 Chief Scientific Officer (Madrid)
🏢 S3 Science Recruitment
📍 Madrid