30 jul
|
Centre For Genomic Regulation
|
Madrid
30 jul
Centre For Genomic Regulation
Madrid
Postdoctoral Researcher - Biodiversity Cell Atlas Database The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a adaptable and efficient administration and by high-end and innovative technologies.
The CRG is recruiting a computational biologist with advanced experience in single-cell data analysis. The position will entail processing of novel and existing single-cell transcriptomic datasets from diverse species across the tree of life, combining comparative genomics, functional gene annotation, and cross-species comparisons to biologically interpret diverse datasets that will be hosted in the BCA database. The candidate will be a part of a highly interdisciplinary team that includes computational, evolutionary and molecular biologists in different groups at CRG (including the Bioinformatics Unit), and this project will be developed jointly with EBI and the Wellcome Sanger Institute.
Cells are the fundamental units of life – underlying cooperative functions in multicellular organisms and complex temporal life cycles in microbial eukaryotes. In recent years, the rapid advance in single-cell genomics technologies, combined with the growing availability of whole-genome sequences, opened up the opportunity to systematically map cell types in diverse organisms.
The goal of the Biodiversity Cell Atlas is to articulate a community effort to build whole-organism cell atlases across the diversity of life, working in a phylogenetically informed way, supported by high-quality genomes, and using shared standards that make comparisons across diversity possible. This coordinated effort should boost our understanding the evolution and diversity of life at cellular resolution: from gene regulatory programs, through cell type molecular profiles,
to biological interactions between species.
At CRG, and together with EBI, we are developing the computational infrastructure to host a multi-species database for the Biodiversity Cell Atlas initiative. This will enable the interactive exploration of cell type molecular maps, gene co-expression profiles across evolution, comparison of cell types across species, and more.
Advanced experience in single-cell data analysis and interpretation
Experience in deep learning methods for single-cell data integration
Proficiency in Python, R, and Linux
Desirable but not required
Experience working with functional genomics data in non-model species
Education and training A PhD in Bioinformatics, Biology, or related disciplines
Languages
You are fluent in English
Technical skills
Hands‑on single‑cell data processing and downstream analysis (clustering, visualization, annotation, etc.)
Capacity to integrate diverse genomics sources (gene annotations, phylogenetic analyses, protein structures, etc.) to support the biological interpretation of single‑cell data
Competences
Highly developed organization and coordination skills
Dedication, motivation, and rigor in scientific pursuits
Capacity to work both independently and as part of a team The Offer – Working Conditions
Contract duration
Technical and scientific activities contract linked to the duration of the project (estimated 18 months).
Estimated annual gross salary
Salary is commensurate with qualifications and consistent with our pay scales.
We provide a highly stimulating environment with state‑of‑the‑art infrastructures, and unique professional career development opportunities.
We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.
The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
📌 Postdoctoral Researcher - Biodiversity Cell Atlas Database (Madrid)
🏢 Centre For Genomic Regulation
📍 Madrid