Territory includes but not limited to: All of EU countries as needed.

Duties and Responsibilities Site engagement and training A cadence of touchpoints with sites on a regular basis. Meeting with sites and presenting at PSVs, SIVs. Retraining as needed (e.g., due to amendments).

Recruitment issues Site identification/recruitment: Meeting with potential sites, in collaboration with CTL, to discuss the program and assess interest. Patient recruitment issues (ongoing oversight): Meeting with sites, in collaboration with CTL, to help understand hurdles and troubleshoot recruitment challenges. Answering questions from sites Help address site medical/clinical questions as a first line for straightforward or previously addressed queries.

Coordinate responses with the Medical Director for more complex or new questions, referencing and updating FAQ as applicable. Ensure the Medical Director is copied on email correspondence for oversight. Assisting with eligibility assessments Help perform eligibility checks or address urgent eligibility questions prior to randomization.

Assisting with query closure Help sites understand requirements to close medical queries, clarify misunderstandings, and provide feedback to improve query clarity. Ensure sufficient information is provided to describe safety events and that all necessary data is gathered. Collaborate with CRAs to request additional assessments for complete evaluation or specialist consultation when required.

Protocol Deviations

Collaborate with CTL to retrain sites, preventing future deviations and addressing misunderstandings. Retention issues Ensure sites follow up with patients lost to follow‑up, taking all appropriate steps and meeting protocol requirements. Missing assessments In PNH studies,



chase missing LDH values rapidly to obtain repeats.

For other studies, assist sites in obtaining key missing assessments (e.g., images, PK samples, biomarker samples). Laboratory reference range Collaborate with CRAs to provide laboratory reference ranges for local laboratory data. Site issues Discuss potential quality issues or concerns with sites; conduct physician-to-physician discussions as first line.

Escalate to general Medical Director if resolution is not straightforward. Mandated meeting obligations Attend CSTs when possible. Weekly meetings or mandatory communication with the Medical Director. Provide clinical assistance and feedback on PI interest in proposed studies at the local level.

Qualifications and Experience MD, Ph D, or Pharm D; MD strongly preferred. 8+ years of industry clinical development experience. Expertise in clinical trials and clinical development. Strong understanding of the Metabolic/Obesity clinical research landscape and implementation of these trials.

Demonstrated ability to develop and maintain excellent working relationships with internal stakeholders, study investigators, and site staff. Ability to work well in cross‑functional and geographically diverse teams. Excellent oral presentation, self‑mandated scientific and technical communication, critical thinking, troubleshooting, and problem‑solving skills.

Self‑initiative, judgment, and positive representation of the company in a compliant manner. Cross‑cultural awareness and fluency in the local language of the primary mandatory country assignment, plus English. Computer skills including Excel, Word, and Power Point.

Willingness to travel up to 65%, which may include local, regional, and international travel. Valid driver’s license.

Regional Medical

Director • Gasteiz, Kingdom Of Spain, ES

📌 Regional medical director (Madrid)
🏢 Regeneron
📍 Madrid