Tecnun - Escuela de Ingeniería - Universidad de Navarra
Technun-School of Engineering, belongs to the University of Navarra. The aim of the School is to contribute to the professional training, scientific and human development of future engineers. Since its creation in the spring of 1961, it has maintained a balance between teaching, research and service to society, making these activities complement each other.
It currently has two sites campus: the older site, located at the university campus in the Ibaeta district, is made up of the laboratory buildings, the teaching and representation building completed in 1989, and a multipurpose building erected in 1996. The other site is located in the Miramon Technology Park and includes classrooms and research laboratories in the areas of Electricity, Electronics and Communications.
Job Description
Title of the project to which the candidate would be incorporated:
"Interpretable deep learning for inferring cellular transcriptional and metabolic changes of genetic perturbations in cancer (PERMET2CAN)"
PID OB-I00 - Call:



Knowledge Generation Projects 2024
Object Of The Position
The main objective of the project is to develop a new framework based on interpretable Deep Learning (DL) to jointly infer transcriptional outcomes and metabolic changes associated with genetic perturbations. The design of the DL model will be guided by a priori biological information and will take into account two simultaneous objectives. Single-cell RNA sequencing (scRNA-Seq) data from perturbation experiments will be used. The proposed framework will allow identifying key cellular responses, transcriptional and metabolic, resulting from genetic perturbations. Understanding transcriptional changes to genetic perturbations is central to identifying genetic interactions in cancer. Similarly, understanding the role of metabolism in cancer not only provides insights into the fundamental biology of cancer, but also highlights potential avenues for the dev

📌 Offer for a predoctoral position linked to project "PERCAN" (España)
🏢 University Of Navarra Finance Society
📍 España