We are currently supporting a leading European pharmaceutical manufacturer on a large-scale SAP S/4HANA transformation, and we're looking for an experienced SAP Project Manager with strong Quality Management expertise to join on a freelance/interim or permanent basis.

This is a high-impact opportunity to take ownership of the quality side of a major pharma S/4HANA programme, leading how SAP QM is designed, validated and delivered in a GxP-regulated environment. You'll work directly with the S/4HANA transformation programme manager.

Role Overview You will lead the SAP QM workstream across the S/4HANA transformation, from design and build through to go-live and hypercare. Pharma and GxP experience is the crucial requirement: you'll make sure quality processes meet regulatory standards, working closely with QA and validation teams on computer system validation, test evidence and release.

You will coordinate QM with connected areas such as production, batch management and MES/LIMS, steer implementation partners and functional consultants, and manage senior stakeholders across the business and IT. A strong emphasis is placed on getting validated quality processes live on time and stable in operation.

Key Responsibilities Lead the SAP QM workstream on the S/4HANA transformation,



from design through to go-live and hypercare

Ensure quality processes meet GxP requirements, working with QA and validation teams on CSV, test evidence and release

Coordinate QM integration with PP-PI, MM, batch management and MES/LIMS

Manage plans, risks, dependencies and SteerCo reporting for the quality stream

Steer system integrators, implementation partners and functional consultants against scope, quality and timelines

Engage senior business, QA and IT stakeholders across the programme

Support cutover, go-live and the handover into operations

Required Experience Proven experience as an SAP Project Manager or QM Workstream Lead on S/4HANA or ECC programmes

Strong SAP QM knowledge within a pharmaceutical or life sciences environment (essential)

Solid GxP background, including GMP, computer system validation (CSV / GAMP 5) and validation documentation

Experience leading teams and managing SI and implementation partners

Strong stakeholder management with senior business and QA leaders

Fluent English and willingness to travel for regular on-site presence

Nice to Have Experience with batch release, stability management, CAPA or MES/LIMS integration

Multi-site or multi-country rollout experience

📌 SAP S/4 HANA Project Manager (Madrid)
🏢 X4 Technology
📍 Madrid