The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.

The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII) .

The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting-edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals : Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers, fostering translational research that integrates basic science with clinical practice in clinical settings.

The Josep Carreras Leukemia Research Institute is looking for a Laboratory Technician for the Chromatin,



metabolism and cell fate group, led by Dr. Marcus Buschbeck in our Can Ruti Campus.

RESEARCH DESCRIPTION

Myeloproliferative neoplasms (MPN), myelodysplastic syndromes (MDS), and acute myeloid leukemia (AML) are related malignant disorders of the bone marrow that disrupt normal blood cell production. MPNs are typically chronic diseases characterized by excessive proliferation of relatively mature myeloid cells, such as in polycythemia vera, essential thrombocythemia, and primary myelofibrosis, and may progress over time to AML. MDS are marked by ineffective and dysplastic hematopoiesis, leading to cytopenias and an increased risk of transformation to AML, particularly in older patients. AML represents the most aggressive end of this disease spectrum and is defined by the rapid accumulation of immature myeloid blasts that replace normal marrow function, causing severe anemia, infections, and bleeding, and requiring urgent treatment.

The Laboratory technician will be involved in several projects in the Buschbeck lab with the focus on multi-omic approaches to identify and characterize new drug targets and validate them in vitro and in vivo.

MAIN RESPONSABILITIES

- Perform tasks within the Buschbeck lab focused on studying blood diseases.





- Support of the lab manager and other group members in multiple research projects.

- Implement experimental methods in molecular biology, biochemistry and genomics (ATAC-seq, RNA-seq etc.).

- Execute in vitro assays using both established cell lines and primary cells.

- Utilize specialized analytical systems, including flow cytometry.

- Conduct procedures with experimental animals following ethical and institutional guidelines.

- Support with experimental mouse colonies maintenance and mouse experimentation-related operations.

WHAT WE NEED

- Professional degree as Laboratory technician (FPGS Laboratorio clínico y biomédico, Anatomia patológica or similar) or Degree (BSc/MSc level) in Biochemistry, Biology, Biotechnology or a related discipline (e.g. Biomedicine, Biomedical Sciences).

- Essential requirement: Accredited training (FELASA or equivalent, e.g. functions A/B/C) for working with laboratory animals, and at least two years of experience in mouse experimentation (do not apply if you don’t have that).

- High motivation for biomedical research.

- Experience in tissue culture (cell lines and primary cells), and molecular biology and biochemistry techniques.

- Fluent English (all protocols and guidelines are in English).

- Experience in basic computer tools: Excel, Word, PowerPoint.

- Pro-active, responsible and well-organized person.

- Attitude to learn and work independently.

- Excellent interpersonal skills and ability to work with other team members.

WHAT WE OFFER

- Temporary contract (Indefinido por actividades científico-técnicas). This contract is supported/financed by “

📌 VAC_93_2026 - LABORATORY TECHNICIAN (España)
🏢 Institut de Recerca contra la Leucèmia Josep Carreras
📍 España