You are here:Home > Junior Bioinformatician– Computational Protein Design and Software InfrastructureJunior Bioinformatician – Computational Protein Design and Software InfrastructureThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a versátil and efficient administration and by high-end and innovative technologies.We are looking for a highly motivated junior bioinformatician to support the computational protein design work of the Design of Biological Systems group (Dr. Luis Serrano) and its software infrastructure. This is a technical support role rather than a research training position: the bioinformatician will work on concrete group needs, in close collaboration with researchers, PhD students and experimental collaborators.Main responsibilities:Validation of a diffusion model for peptide generation:run benchmarks, compare generated peptides using structural and energetic criteria (FoldX, AlphaFold3, Boltz) and report results to the team.Automation of molecule parameterisation in FoldX:develop and maintain scripts and pipelines that generate FoldX parameters for new small molecules and non-standard residues.Software maintenance and distribution:take charge of compiling, maintaining and version-controlling the group’s development and distribution infrastructure, including FoldX (multiplatform builds, dependency updates, portable binaries and release support).About the teamOur group aims to quantitatively understand biological systems and to rationally design and modify their behaviour. We develop software that spans biological databases to structural modelling at the atomic level, including the FoldX suite (foldxsuite.Crg.Es) and ModelX (modelx.Crg.Es).



We combine these computational tools with experiments to validate our predictions.Whom would we like to hire?Professional experienceMust HaveYou have a basic understanding of protein structure and structural biologyYou have working knowledge of Python and of the Linux command lineDesirable but not required/ Nice to haveC++ programming, or willingness to learn it on the jobVersion control (Git) and build tools (CMake, Make, compilers on Linux and macOS)Experience with HPC clusters and job schedulersExperience with structural modelling tools (FoldX, AlphaFold, Boltz, Rosetta or similar)Experience running or evaluating machine-learning modelsSQL databasesEducation and trainingYou hold a bachelor’s or master’s degree in bioinformatics, Biotechnology, Biochemistry, Chemistry, Computer Science or a related fieldLanguagesYou are fluent in English, spoken and writtenTechnical skillsYou can write and maintain scripts that automate computational workflowsCompetencesHighly developed organisational skillsReliability and attention to detailAbility to document your work clearlyTeam player in an interdisciplinary environmentThe Offer – Working ConditionsContract duration:Technical and scientific activities contract linked to the project (with an estimated duration of 1 year).Estimated annual gross salary:Salary is commensurate with qualifications and consistent with our pay scales.Target start date:January 2026.We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .We offer andpromote a diverse and inclusive environmentand welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.TheCRG is committed to reconcile a work and family lifeof its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.Funded by the European Union (ERC, SafeDelivery, Grant Agreement Nº 101266773)”#J-18808-Ljbffr

📌 Junior Bioinformatician – Computational Protein Design And Software Infrastructure (Madrid)
🏢 Crg
📍 Madrid