Johnson & Johnson seeks a Principal Scientist in Biophysics/Biochemistry to develop and execute Surface Plasmon Resonance and biochemical assays supporting Design-Make-Test-Learn discovery workflows. The role focuses on assay innovation, automation integration, and cross-functional collaboration to accelerate hit identification and lead optimization.

Responsibilities

- Design and execute SPR and biochemical assays to support hit validation and lead optimization across discovery programs
- Generate and interpret kinetic, affinity, and thermodynamic data to guide structure-activity relationships and project decisions
- Develop automated biophysical and biochemical workflows to increase experimental scale, consistency, and throughput
- Partner with chemistry, biology, computational sciences, automation, and platform teams to integrate capabilities into scalable discovery workflows




- Lead cross-functional project teams and act as an independent scientist identifying opportunities and solving technical challenges

Requirements

- Ph.D. in Biophysics, Biochemistry, Structural Biology, or related discipline
- 8+ years developing and executing biophysical and biochemical assays in pharma, biotech, or academic research
- Hands-on expertise with SPR and complementary biophysical platforms
- Experience with assay automation, high-throughput experimentation, or laboratory robotics
- Strong understanding of protein-ligand interactions, kinetics, and thermodynamics
- Demonstrated ability to interpret complex datasets and translate results into drug discovery decisions
- Excellent scientific communication and collaborative problem-solving skills

Compensation: €63,700–€109,480 base

📌 Principal Scientist, Biophysics/Biochemical DMTL Automation (España)
🏢 Johnson & Johnson
📍 España