Job Reference 480_26_LS_CB_R2 Position Postdoctoral Researcher – Protein design and structural bioinformatics (R2) Closing Date Tuesday, 10 November, 2026 Reference: 480_26_LS_CB_R2 Job title: Postdoctoral Researcher – Protein design and structural bioinformatics (R2) About BSC The Barcelona Supercomputing Center
- Centro Nacional de Supercomputación (BSC-CNS) is the leading supercomputing center in Spain. It houses MareNostrum, one of the most powerful supercomputers in Europe, was a founding and hosting member of the former European HPC infrastructure PRACE (Partnership for Advanced Computing in Europe), and is now hosting entity for EuroHPC JU, the Joint Undertaking that leads large-scale investments and HPC provision in Europe. The mission of BSC is to research, develop and manage information technologies in order to facilitate scientific progress. BSC combines HPC service provision and R&D; into both computer and computational science (life, earth and engineering sciences) under one roof, and currently has over 1000 staff from 60 countries. Look At The BSC Experience BSC-CNS YouTube Channel Let's stay connected with BSC Folks We are particularly interested for this role in the strengths and lived experiences of women and underrepresented groups to help us avoid perpetuating biases and oversights in science and IT research. In instances of equal merit, the incorporation of the under-represented sex will be favoured. We promote Equity, Diversity and Inclusion, fostering an environment where each and every one of us is appreciated for who we are, regardless of our differences. If you consider that you do not meet all the requirements, we encourage you to continue applying for the job offer. We value diversity of experiences and skills, and you could bring unique perspectives to our team. Context And Mission The Computational Biology group, led by ICREA professor Alfonso Valencia, is seeking a Postdoctoral Researcher to work in the context of structural bioinformatics. The Life Sciences Department at BSC integrates the research of senior scientists working on various aspects of computational biology, ranging from bioinformatics for genomics to computational biochemistry and text mining. The Computational Biology group (http://life.bsc.es/compbio) is involved in multiple projects covering a wide range of topics including protein design, multilayer network modeling, epigenomics, and computational systems biology. The selected candidate will work in collaboration with senior researchers in the Computational Biology group of the Life Sciences Department, as well as with other research groups at BSC. The work aligns with the group's research lines on personalized medicine, protein design and protein structure-function analysis. The Researcher will have access to a highly sophisticated HPC environment and cutting-edge computational infrastructures, collaborating with experts at both national and international levels.

Key responsibilities
include developing and applying ML/AI methods for protein design, protein-protein interaction predictions, and stability analysis of protein structures in response to single or multiple amino acid mutations. Key Duties
• Participate in national and European research projects focused on structural bioinformatics and protein design.
• Develop and apply cutting-edge ML/AI methods for protein design and the study of relevant biological problems involving proteins.
• Investigate protein-protein interaction networks across different organisms using coevolution-based and AI-based approaches.
• Attend scientific conferences, workshops, and training sessions to advance professional development.




• Contribute to grant writing and funding proposals.
• Establish and maintain collaborations with national and international researchers. Requirements
• Education
• Ph.
D. in Structural Bioinformatics or related field.
• Essential Knowledge and Professional Experience
• Proven experience in protein sequence/structure modeling and analysis.
• Hands-on expertise in ML/AI methodologies applied to biology.
• Programming skills in Python.
• Additional Knowledge and Professional Experience
• Experience in protein design and synthetic biology projects.
• Expertise in molecular dynamics simulations.
• Knowledge of complex networks analysis (graph representation, graph analytics).
• Solid foundation in traditional statistics and ML methods.
• Familiarity with HPC environments.
• Fluency in spoken and written English.
• Competences
• Capacity to initiate and explore new research directions.
• Good communication and presentation skills.
• Ability to work both autonomously and within a team.
• Interpersonal aptitudes and collaborative attitudes. Conditions
• The position will be located at BSC within the Life Sciences Department
•

We offer
a full-time contract (35h/week), a good working environment, a highly stimulating environment with state-of-the-art infrastructure, versátil

working hours
, extensive training plan, restaurant tickets, private health insurance, support to the relocation procedures
• Duration: Open-ended contract due to technical and scientific activities linked to the project and budget duration
• Holidays: 22 days of holidays + 6 personal days + 24th and 31st of December per our collective agreement
•

Salary:

we offer
a competitive salary commensurate with the qualifications and experience of the candidate and according to the cost of living in Barcelona
• Starting date: 16/11/2026 Applications procedure and process All applications must be submitted via the BSC website and contain:
• A full CV in English including contact details
• A cover/motivation letter with a statement of interest in English, clearly specifying for which specific area and topics the applicant wishes to be considered. Additionally, two references for further contacts must be included. Applications without this document will not be considered. Development of the recruitment process The selection will be carried out through a competitive examination system ("Concurso-Oposición"). The recruitment process consists of two phases:
• Curriculum Analysis: Evaluation of previous experience and/or scientific history, degree, training, and other professional information relevant to the position.
- 40 points
• Interview phase: The highest-rated candidates at the curriculum level will be invited to the interview phase, conducted by the corresponding department and Human Resources. In this phase, technical competencies, knowledge, skills, and professional experience related to the position, as well as the required personal competencies, will be evaluated.
- 60 points. A minimum of 30 points out of 60 must be obtained to be eligible for the position. The recruitment panel will be composed of at least three people, ensuring at least 25% representation of women.



In accordance with OTM-R principles, a gender-balanced recruitment panel is formed for each vacancy at the beginning of the process. After reviewing the content of the applications, the panel will begin the interviews, with at least one technical and one administrative interview. At a minimum, a personality questionnaire as well as a technical exercise will be conducted during the process. The panel will make a final decision, and all individuals who participated in the interview phase will receive feedback with details on the acceptance or rejection of their profile. At BSC, we seek continuous improvement in our recruitment processes. For any suggestions or comments/complaints about our recruitment processes, please contact [email protected]. For more information, please follow this link. Deadline The vacancy will remain open until a suitable candidate has been hired. Applications will be regularly reviewed and potential candidates will be contacted. OTM-R principles for selection processes BSC-CNS is committed to the principles of the Code of Conduct for the Recruitment of Researchers of the European Commission and the Open, Transparent and Merit-based Recruitment principles (OTM-R). This is applied for any potential candidate in all our processes, for example by creating gender-balanced recruitment panels and recognizing career breaks etc. BSC-CNS is an equal opportunity employer committed to diversity and inclusion. We are pleased to consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or any other basis protected by applicable state or local law. For more information follow this link Application Form You are applying for the following job offer Name and Surname
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📌 Postdoctoral Researcher – Protein design and structural bioinformatics (Barcelona)
🏢 Barcelona Supercomputing Center
📍 Barcelona