Organisation/Company Institut d'Investigació Biomèdica Sant Pau Research Field Other Researcher Profile Other Profession Positions Bachelor Positions Application Deadline 30 Oct 2026
- 15:00 (Europe/Madrid) Country Spain Type of Contract Permanent Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Call for applications for a T4A Junior Higher Technician position within the Department of Hematologic Oncology and Transplantation (Cellular Immunotherapy and Gene Therapy Group). Application deadline: 30 October 2026 at 3:00 p.m. About the Unit / Research Group The Cellular Immunotherapy and Gene Therapy Group (GITG) within the Hematology Department focuses on the study of genetically modified T cells expressing chimeric antigen receptors (CARs) and their clinical application in patients with hematological malignancies. The GITG at IR Sant Pau is a well-established research group that develops and manufactures advanced CART therapy products for the treatment of patients with lymphoid hematological malignancies. Our group initiated a first-in-Europe Phase I clinical trial using CART30 cells (HSP-CAR30) for patients with Hodgkin lymphoma, and the Phase II study is currently ongoing. During 2024, a second clinical trial was launched in patients with refractory B-cell lymphomas using selected memory T cells expressing CAR19 (HSP-CAR19M). Both HSP-CAR30 and HSP-CAR19M products are fully manufactured at Sant Pau by the GITG according to Good Manufacturing Practice (GMP) standards. Current research lines focus on:
* Investigating the antitumor efficacy of memory T-cell subsets.
* Studying the antitumor efficacy of genetically modified stem memory T cells expressing CARs.
* Developing innovative fourth-generation CARs targeting antigens expressed in hematological malignancies.




* Developing academic CART immunotherapy clinical trials for patients with lymphoid malignancies.
* Minimum qualification required: Higher Education degree (Bachelor's Degree, University Diploma, or equivalent).
* Oral and written proficiency in the two official languages of Catalonia or, alternatively, the selected candidate must demonstrate, or commit to acquiring within a maximum period of one year, an adequate command of both official languages.
* Intermediate level of English.
* Intermediate level of office software tools (Excel, Word, PowerPoint, etc.). The following will be valued
* Knowledge of immunology, immunotherapy, tumour immunology assays, and molecular biology techniques (qPCR).
* Experience in the development of CART therapies.
* Experience in flow cytometry and cell culture techniques. Duties
* Manufacturing advanced therapy medicinal products (CART cells) in compliance with GMP standards.
* Manufacturing lentiviral vectors under GMP regulations within the Advanced Therapies Unit of IR Sant Pau (Clean Room Facility).
* Inventory control and materials management in accordance with GMP requirements.
* Drafting and preparing protocols and records associated with GMP manufacturing of lentiviral vectors and CART cells.
* Supporting quality control activities for GMP CART-cell manufacturing, including flow cytometry, cytotoxicity assays, and qPCR analyses.
* Preparing reports on incidents and non-conformities related to the assigned work environment.
* Supporting equipment control, maintenance, and calibration activities.
* Performing equipment maintenance and review tasks.

We Offer
* Permanent contract linked to the research line: “CART Therapy for Hematological Cancer.”
* Annual workload of 1,627.5 hours (37.5 hours per week).
* Salary according to the applicable collective agreement.
* Integration into the Hematologic Oncology and Transplantation Group. The deadline for submitting applications is 30 October 2026 at 3:00 p.m. #J-18808-Ljbffr

📌 2026/141: 1A Junior Higher Technician (España)
🏢 Institut d'Investigacio Biomedica Sant Pau
📍 España