Company Overview Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. The Federated Registry Data scientist will contribute to the design, development and operation of a multi-country federated registry platform based on the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM), in collaboration with specialized vendors for Extract-Transform-Load (ETL), hosting, and federated analyses. The role will serve as a primary point of contact between Rhythm, the selected vendors, and participating registries for data-related activities. The Data Scientist will oversee the local registry data collection (mapping, transformation, quality-check) and the federated analyses specifications and outputs within a federated OMOP CDM-based environment provided and maintained by the vendors. Federated analyses Oversee data collection, data quality check, ETL logic and data mapping to OMOP CDM Lead preparation and review of the statistical analysis plan, cohort definitions, variable definitions,



and federated query specifications supported and executed by the vendors based on research questions proposed by the Scientific Committee, the participating centers or internally Collaborate with the vendor on source data review, OMOP mapping, ETL logic, and data quality checks, helping to identify, prioritize, and resolve quality issues Help with data-related questions raised by the vendor and coordinate timely responses from centers when local input is required Ensure that data-related discussions remain aligned with Rhythm’s scientific objectives, project scope, timelines, and budget Support sites in understanding project data requirements, minimum datasets, expected formats, timelines, and quality control processes Coordinate with sites and the vendor to investigate data quality issues such as missing data, inconsistent values, duplicate records, etc. Advanced degree in Life Sciences, Data Science, Information Systems, or an equivalent scientific or technical discipline Strong experience with healthcare data sources, including clinical registries, electronic health records, claims databases, healthcare databases, and real-world evidence projects Strong proficiency in R and/or Python Strong communication and interpersonal skills, capable of engaging with senior leadership and key stakeholders. Fluent in English This role is home office based. Rhythm operates in a hybrid-work model. We are a dynamic and growing general team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare melanocortin-4 receptor (MC4R) pathway diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.

📌 Senior Data Scientist, hibrido (España)
🏢 Rhythm Pharmaceuticals
📍 España