Site Leader (Senior Director / VP) – mRNA/LNP CDMOCDC General Solutions is partnering with a growing CDMO specialising in nucleic acid and advanced therapy manufacturing, including DNA, RNA and mRNA/LNP. Following continued investment, the company is appointing a Site Leader to drive operational execution as it scales.Reporting to the Chief Business Officer, the Site Leader will run day-to-day operations at the Bilbao site, with responsibility for manufacturing, quality control, supply chain and facilities. You'll turn executive direction into clear operating plans, lead and develop site teams, and make sure all activity meets GMP, safety and customer commitments.This is a hands-on operational leadership role. Enterprise strategy, commercial ownership and P&L; sit with the executive team.Key responsibilitiesLead site-wide execution across manufacturing, QC, supply chain and facilities, setting priorities and making ownership clearTurn executive direction into operating plans, milestones and resourcing decisionsCoordinate production schedules, materials, staffing, testing and equipment readiness to meet customer timelinesRun a practical management cadence covering KPIs, risk escalation and issue resolution, without unnecessary bureaucracyOversee GMP manufacturing readiness and execution for DNA, mRNA, saRNA and LNP programmesProvide site-level oversight of technology transfer, scale-up, qualification and validation readiness, partnering with MSAT, Process Development, Engineering and QualityMake sure technical teams have clear priorities and resources for mRNA production,



purification and LNP formulationDrive robust, reproducible processes and continuous improvementPartner with QA on GMP compliance, inspection readiness, data integrity, deviations, CAPA and change controlOversee EHS, facility and equipment availability, and preventive maintenanceManage site expenditure, capacity planning and capital projects within approved budgetsLead, coach and develop site managers and multidisciplinary teams, with a visible, hands-on presence on the manufacturing floorWork effectively across site functions and corporate matrix teamsPartner with commercial leadership to align demand with capacity and deliver customer commitmentsSupport customer-facing technical discussions and external technology transfersEscalate material risks to quality, safety, capacity or delivery promptly, with clear recommendationsRequirements10-15 years in pharmaceutical, biotech or CDMO operations, including 5+ years leading manufacturing teams or multiple operational functionsProven GMP manufacturing leadership, including exposure to QC, supply chain and facilitiesStrong knowledge of pharmaceutical quality systems, technology transfer, scale-up and site readinessExperience in biologics, nucleic acids, mRNA/LNP or advanced therapies preferred; direct LNP experience is highly valuedFamiliarity with process validation, investigations, qualification and analytical controls is advantageousDegree in engineering, biotechnology, life sciences, pharmaceutical sciences or a related fieldFluent Spanish and professional English; experience leading teams in Spain strongly preferred#J-18808-Ljbffr

📌 Site Lead (Madrid)
🏢 CDC Global Solutions
📍 Madrid