JOB DESCRIPTION We are offering a fully funded PhD position in statistical genomics and precision medicine, based at the Institut de Recerca Germans Trias i Pujol (IGTP, Badalona), under the supervision of Dr. Sílvia Bonàs-Guarch (PI), with co-supervision by Dr. Anne L. Madsen, at the Steno Diabetes Center Aarhus (Aarhus University Hospital, Denmark).The position is funded through the Spanish "Proyectos de Generación de Conocimiento" call (PEICTI 2024-2027), via an FPI predoctoral contract, and is part of a newly funded research project on the molecular mechanisms underlying beta-cell dysfunction in type 2 diabetes (T2D), aimed at improving patient stratification and treatment optimisation using large-scale human genomics and exposome data. ProjectThe PhD candidate will develop mechanism-specific polygenic scores for pancreatic islet beta-cell dysfunction, leveraging pleiotropy and regulatory genomics and generative machine-learning approaches, and will integrate them with exposure-based scores to build a joint genetic-exposure liability model for T2D subtyping.



The project moves beyond integral genetic risk models towards biologically-grounded interpretable predictor models of T2D heterogeneity, with direct applications in patient stratification and precision medicine. The student will work with large-scale resources including UK Biobank, in-house national GCAT cohort, and Danish population cohorts. EnvironmentThe candidate will join theMedical Genomics and Precision Medicine for T2Dresearch line, led by Dr. Sílvia Bonàs-Guarch, within the Genomes for Life-GCAT Lab, supervised by Dr. Rafa de Cid. This research line focuses on understanding the molecular and environmental determinants that influence the risk and progression of type 2 diabetes. Within the broader GCAT Lab, the student will have direct access to population genomics infrastructure, computational resources and genetics and exposome expertise. Co-supervision and close collaboration with Dr. Anne L. Madse

📌 2026_130_PHD POSITION IN STATISTICAL GENOMICS AND PRECISION MEDICINE IN TYPE 2 DIABETES (España)
🏢 IGTP Retreat
📍 España