The Pluripotency for organ regeneration Group at the Institute for Bioengineering of Catalonia (IBEC) is looking for a Post-doctoral Researcher to conduct her/his postdoctoral training whose main objective is to develop robust and reproducible human organoid models to study tissue development as well as genetic and systemic disease conditions.
Main tasks and responsibilities:
• Development of renal, cardiac and neural derivatives (among others) from human pluripotent stem cells (hPSCs) in 2D and 3D cell culture settings making use of engineering approaches to establish new controlled microenvironments.
• Development of genome engineered hPSCs to model disease mechanisms.
• Development and Implementation of quantitative and qualitative assays to monitor molecular and metabolic changes as well as cell-cell interactions during organoid development in 2D and 3D cell culture settings.
Requirements for candidates:
Essential:
• PhD in the field of biology, biotechnology, biomedical engineering, biomedicine or similar areas
• Proved knowledge on culture and differentiation of human pluripotent stem cells (hPSC) (specifically on methodologies to derive hPSC-organoids will be a plus), confocal microscopy and quantitative image analysis, as well as molecular biology techniques.
• Experience in bioengineering technologies such as microfabrication, biomaterials and organ-on-chip approaches.
• Competencies and skills: Communication, Teamwork and collaboration, Commitment, Proactivity, Integrity, Critical and Analytical thinking.
• High level of English
Advantageous:
• Experience in developing custom made scripts for image processing and quantification.
• Experience in CRISPR/Cas9 genome editing
We Offer:
• Number of available positions: 1
• Starting date: November
• Working conditions:
• Full- time Open-ended contract due to technical and scientific activities linked to the project and budget duration.
• Measures to reconcile work an
📌 Postdoctoral Researcher (Barcelona)
🏢 Institute for Bioengineering of Catalonia (IBEC)
📍 Barcelona
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