16 oct
|
Institute for Bioengineering of Catalonia (IBEC)
|
España
16 oct
Institute for Bioengineering of Catalonia (IBEC)
España
The Spatial Biotechnology Group is looking for a talented and highly motivated Postdoctoral Researcher to work at the interface between experimental and computational biology, building automated, closed-loop workflows. The position is part of our effort to understand how cells spatially organize to drive solid tumor development, and it brings together three fast-moving fronts: spatial proteomics, lineage tracing technologies, and laboratory automation. The successful candidate will design and execute robot-driven experiments and will analyze the resulting spatial data, closing the loop between experimental design, automated execution and data-driven decisions about what to run next. This is an opportunity for a hybrid scientist who wants to help define how a self-driving biology laboratory works. Main tasks and responsibilities: * Design, build and validate automated liquid-handling workflows on an Opentrons Flex platform (Python API). * Establish and run spatial proteomics on in vitro co-cultures, engineered 3D tumor models and tissue sections.
* Implement clonal barcoding and lineage tracing readouts, including in situ detection and debarcoding of individual clones. * Scale perturbation experiments to high-throughput formats, integrating robotics, automated microscopy and sample tracking into reproducible end-to-end pipelines. * Develop and apply computational pipelines for image processing, cell segmentation, debarcoding and spatial statistics. * Close the experimental-computational loop, using analysis results to guide the design of the next round of automated experiments (design of experiments, active learning). * Ensure reproducibility and FAIR data practices: version-controlled code, documented protocols, structured metadata and open sharing of tools. * Present results at internal meetings and international conferences, and contribute to manuscript preparation. * Apply for competitive postdoctoral fellowships and, later, for independent career awards, with fu
📌 Postdoctoral Researcher (España)
🏢 Institute for Bioengineering of Catalonia (IBEC)
📍 España