Overview The Höpfler lab at the Institute for Genomic Regulation (CRG) is offering a postdoctoral position focused on RNA biology and gene regulation. The role involves leading a project to develop sequencing methods that identify messenger RNA (mRNA) decay substrates and to decipher the mechanisms of degradation. Responsibilities - Develop sequencing approaches to identify peptide-mediated mRNA decay (PMD) substrates - Perform bioinformatic data analysis and visualization of sequencing datasets - Identify and mechanistically characterize PMD candidate substrates - Present data at international conferences and prepare manuscripts - Lead and manage international collaborations - Actively participate in lab meetings and contribute to a culture of technical excellence and scientific curiosity Qualifications We are particularly interested in candidates with a hybrid wet‑lab and bioinformatics background who have a track record in RNA biology or gene regulation. Must Have - Bioinformatics experience in the analysis of (RNA)



sequencing data - Experience with common laboratory techniques in cell and molecular biology - PhD degree (or expected to complete the degree before starting) in cell/molecular biology, bioinformatics, or a related field - Strong publication record commensurate with career stage - Ability to pursue research projects independently Desirable - Experience with massively parallel reporter assays (MPRAs) - Experience exploring mRNA turnover on a transcriptome‑wide scale - Background in RNA biology, translational control, or related areas Languages - Fluency in written and spoken English Computer Skills - Proficiency with data analysis software (R, Python) - Experience using high‑performance computing clusters - Advanced MS Office experience Competences - Curiosity and critical thinking - Rigor, organization, and autonomy - Strong analytical, interpersonal, and communication skills Offer – Working Conditions - Contract duration: Technical and scientific act

📌 Postdoc in the Dynamics of Protein Synthesis and RNA Decay Lab (Barcelona)
🏢 Somma
📍 Barcelona