Overview The Höpfler lab at the Institute for Genomic Regulation (CRG) is offering a postdoctoral position focused on RNA biology and gene regulation. The role involves leading a project to develop sequencing methods that identify messenger RNA (mRNA) decay substrates and to decipher the mechanisms of degradation. Responsibilities * Develop sequencing approaches to identify peptide-mediated mRNA decay (PMD) substrates * Perform bioinformatic data analysis and visualization of sequencing datasets * Identify and mechanistically characterize PMD candidate substrates * Present data at international conferences and prepare manuscripts * Lead and manage international collaborations * Actively participate in lab meetings and contribute to a culture of technical excellence and scientific curiosity Qualifications We are particularly interested in candidates with a hybrid wet‑lab and bioinformatics background who have a track record in RNA biology or gene regulation. Must Have * Bioinformatics experience in the analysis of (RNA)



sequencing data * Experience with common laboratory techniques in cell and molecular biology * PhD degree (or expected to complete the degree before starting) in cell/molecular biology, bioinformatics, or a related field * Strong publication record commensurate with career stage * Ability to pursue research projects independently Desirable * Experience with massively parallel reporter assays (MPRAs) * Experience exploring mRNA turnover on a transcriptome‑wide scale * Background in RNA biology, translational control, or related areas Languages * Fluency in written and spoken English Computer Skills * Proficiency with data analysis software (R, Python) * Experience using high‑performance computing clusters * Advanced MS Office experience Competences * Curiosity and critical thinking * Rigor, organization, and autonomy * Strong analytical, interpersonal, and communication skills Offer – Working Conditions * Contract duration: Technical and scientific act

📌 Postdoc in the Dynamics of Protein Synthesis and RNA Decay Lab (España)
🏢 Somma
📍 España