Proyecto de Generación de Conocimiento 2025 by the Spanish Ministry of Science, Innovation and Universities
Introduction to the vacant position:The Biosensors for Bioengineering Group is looking for a predoctoral researcher to develop a biotechnological project to develop a liver senescence model. The contract will be within the framework of a national project, whose objective is to determine the liver’s effect on the ageing process. The PhD project will be conducted in the framework of the project entitled: “Modelización in vitro del envejecimiento sistémico iniciado por el hígado: mecanismos de senescencia celular y comunicación interorgánica” – (HEPAGING)
This fellowship is associated with the research project Generación de Conocimiento, funded by the Spanish Ministry of Science, Innovation and Universities.
Main tasks and responsibilities:
- Development of 3D in vitro liver tissue models to study cellular senescence and ageing.
- Application of tissue engineering and biomaterials approaches for the generation of physiologically relevant liver models.




- Cell culture and differentiation of human liver cells and/or liver-derived cellular models.
- Development and optimisation of 3D cell culture and cell encapsulation strategies.
- Characterisation of liver function and senescence, including molecular, biochemical and imaging-based approaches.
- Investigation of inter-organ communication mechanisms and liver-mediated systemic ageing processes.
- Integration of biosensors and analytical technologies for real-time monitoring of tissue function and secreted biomarkers.
- Analysis and interpretation of experimental data using quantitative and statistical approaches.
- Contribution to the dissemination of results through scientific publications, conferences and project reports.
- Collaboration within a multidisciplinary and international research environment.

Requirements for candidates:Essential:
- BSc and MSc in biology, biotechnology, biomedical engineering, biomedic

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