14 oct
|
Institute for Bioengineering of Catalonia (IBEC)
|
Cataluña
14 oct
Institute for Bioengineering of Catalonia (IBEC)
Cataluña
The Spatial Biotechnology Group is looking for a talented and highly motivated Postdoctoral Researcher to work at the interface between experimental and computational biology, building automated, closed-loop workflows. The position is part of our effort to understand how cells spatially organize to drive solid tumor development, and it brings together three fast-moving fronts: spatial proteomics, lineage tracing technologies, and laboratory automation. The successful candidate will design and execute robot-driven experiments and will analyze the resulting spatial data, closing the loop between experimental design, automated execution and data-driven decisions about what to run next. This is an opportunity for a hybrid scientist who wants to help define how a self-driving biology laboratory works. Main tasks and responsibilities:
- Design, build and validate automated liquid-handling workflows on an Opentrons Flex platform (Python API).
- Establish and run spatial proteomics on in vitro co-cultures, engineered 3D tumor models and tissue sections.
- Implement clonal barcoding and lineage tracing readouts, including in situ detection and debarcoding of individual clones.
- Scale perturbation experiments to high-throughput formats, integrating robotics, automated microscopy and sample tracking into reproducible end-to-end pipelines.
- Develop and apply computational pipelines for image processing, cell segmentation, debarcoding and spatial statistics.
- Close the experimental-computational loop, using analysis results to guide the design of the next round of automated experiments (design of experiments, active learning).
- Ensure reproducibility and FAIR data practices: version-controlled code, documented protocols, structured metadata and open sharing of tools.
- Present results at internal meetings and international conferences, and contribute to manuscript preparation.
- Apply for competitive postdoctoral fellowships and, later, for independent career awards, with fu
📌 Postdoctoral Researcher Full-time (Cataluña)
🏢 Institute for Bioengineering of Catalonia (IBEC)
📍 Cataluña