Institute for bioengineering of Catalonia, IBEC
Organisation/Company Institute for bioengineering of Catalonia, IBEC Research Field Biological sciences Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 30 Oct 2026 - 23:59 (Europe/Madrid) Country Spain Type of Contract Temporary Job Status Full-time Hours Per Week 37.5 Is the job funded through the EU Research Framework Programme? Other EU programme Is the Job related to staff position within a Research Infrastructure? No
Offer Description
Introduction to the vacant position:
The Enzyme Sensors and Chemical Probes group is looking for a motivated Ph.D. student to dissect post-translational modifications (PTMs) across the microtubule network of the cell, by developing new inhibitors and fluorescent sensors of metalloenzymes. This positions fit within the scope of the project CHEMTUBIO (ERC Starting Grant), and within our overall aim of revealing disease mechanisms through the development of imaging tools and chemical probes, leading up to methods for translatable drug discovery.




Main tasks and responsibilities:
- Synthetic organic chemistry: develop small molecule- and peptide-based inhibitors of metalloenzymes using in-solution and solid-phase chemistry
- Enzyme assay development: investigate enzyme activity in vitro using purified recombinant proteins
- Live cell imaging: study the spatiotemporal regulation of microtubule PTMs through selective enzyme inhibition and activity sensing in cell culture
- Training activities:attend scientific seminars, as well as courses in scientific and transversal skills, as part of the doctoral training
- Outreach: disseminate research findings at international conferences and through publications

Requirements for candidates:
- Education: M.Sc. degree in Medicinal Chemistry, Chemical Biology, Biochemistry, or a related field
- Technical expertise: demonstrated expertise in organic chemistry and/or biochemistry techniques
- Transversal skills

📌 Ph.D. student in Medicinal Chemistry (España)
🏢 Institute for Bioengineering of Catalonia (IBEC)
📍 España