Proyecto de Generación de Conocimiento 2025 by the Spanish Ministry of Science, Innovation and UniversitiesIntroduction to the vacant position:The Biosensors for Bioengineering Group is looking for a predoctoral researcher to develop a biotechnological project to develop a liver senescence model. The contract will be within the framework of a national project, whose objective is to determine the liver’s effect on the ageing process. The PhD project will be conducted in the framework of the project entitled: “Modelización in vitro del envejecimiento sistémico iniciado por el hígado: mecanismos de senescencia celular y comunicación interorgánica” – (HEPAGING)This fellowship is associated with the research project Generación de Conocimiento, funded by the Spanish Ministry of Science,



Innovation and Universities.Main tasks and responsibilities:Development of 3D in vitro liver tissue models to study cellular senescence and ageing.Application of tissue engineering and biomaterials approaches for the generation of physiologically relevant liver models.Cell culture and differentiation of human liver cells and/or liver-derived cellular models.Development and optimisation of 3D cell culture and cell encapsulation strategies.Characterisation of liver function and senescence, including molecular, biochemical and imaging-based approaches.Investigation of inter-organ communication mechanisms and liver-mediated systemic ageing processes.Integration of biosensors and analytical technologies for real-time monitoring of tissue function and secreted biomarkers.Analysis and interpretation of experimental data using quantitative and statistical approaches.Contribution to the dissemination of results through scientific publications, conferences and project reports.Collaboration within a multidisciplinary and international research environment.Requirements for candidates:Essential:BSc and MSc in biology, biotechnology, biomedical engineering, biomedicine or similar areasCandidates should

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