The Barcelona Institute for Integral Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level. Research is organized in five programs: Climate, Air Pollution, Nature and Urban Health; Environment and Health over the Lifecourse; Global Viral and Bacterial Infections; Malaria and Neglected Parasitic Diseases and Maternal Child and Reproductive Health. ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.

WHAT WE ARE LOOKING FOR
ISGlobal is seeking a Software Engineer to implement and maintain a platform for episignatures (EPIFLARE - Diagnosis of rare neurodevelopmental disorders using integrated epigenomics within a secure federated learning framework). We aim to consolidate,



optimize and clinically validate a privacy-preserving platform that improves the diagnosis of neurodevelopmental and rare disorders.
The candidate will join the Bioinformatics Research Group in Epidemiology (BRGE), led by Dr Juan Ramón Gonzalez, within the Environment and Health over the Lifecourse research programme. The group develops reproducible, secure methods for analysing sensitive clinical and omics data in multidisciplinary settings.
EPI-FLARE enables federated access to clinical and epigenomic data held at participating hospitals. Its architecture combines Opal and DataSHIELD with the dsHPC infrastructure, a request-handling API, Slurm-based execution in R and Python environments, result caching, audit trails, secure R Shiny visualization and a web-based administration panel. Only non-disclosive outputs leave each institution.
The Software Engineer will optimize analytical pipelines for epimutations, episignatures, co

📌 Software Engineer EPI-FLARE (España)
🏢 Barcelona Institute for Global Health (ISGlobal)
📍 España