Introduction to the vacant position:
The Spatial Biotechnology Group is looking for a talented and highly motivated Postdoctoral Researcher to work at the interface between experimental and computational biology, building automated, closed-loop workflows. The position is part of our effort to understand how cells spatially organize to drive solid tumor development, and it brings together three fast-moving fronts: spatial proteomics, lineage tracing technologies, and laboratory automation. The successful candidate will design and execute robot-driven experiments and will analyze the resulting spatial data, closing the loop between experimental design, automated execution and data-driven decisions about what to run next. This is an opportunity for a hybrid scientist who wants to help define how a self-driving biology laboratory works.
Main tasks and responsibilities:
• Design, build and validate automated liquid-handling workflows on an Opentrons Flex platform (Python API).
• Establish and run spatial proteomics on in vitro co-cultures, engineered 3D tumor models and tissue sections.




• Implement clonal barcoding and lineage tracing readouts, including in situ detection and debarcoding of individual clones.
• Scale perturbation experiments to high-throughput formats, integrating robotics, automated microscopy and sample tracking into reproducible end-to-end pipelines.
• Develop and apply computational pipelines for image processing, cell segmentation, debarcoding and spatial statistics.
• Close the experimental-computational loop, using analysis results to guide the design of the next round of automated experiments (design of experiments, active learning).
• Ensure reproducibility and FAIR data practices: version-controlled code, documented protocols, structured metadata and open sharing of tools.
• Present results at internal meetings and international conferences, and contribute to manuscript preparation.
• Apply for competitive postdoctoral fellowships and, later, f

📌 Postdoctoral Researcher (Barcelona)
🏢 Institute for Bioengineering of Catalonia (IBEC)
📍 Barcelona