Make your mark for patientsWe are looking for a Principal Scientist, Non-Clinical PKPD, who is innovative and agile to join us in our Clinical Development Sciences Group, based at the R&D; site in Slough, UK, then Windlesham, Surrey (2027).About the role The Non-Clinical PKPD group sits within the Quantitative Clinical Pharmacology (QCP) function of Early Clinical Development & Translational Science (ECD-TS) Department. Our goal is to use integrated quantitative approaches as an essential strategic driver from target to market to bring differentiated solutions to patients. We are driving the quantitative integrated strategy of pharmacokinetics and pharmacology (e.g. PKPD, Systems modelling and clinical pharmacology/pharmacometrics) together with DMPK activities throughout the entirety of the lifetime of projects, from target identification through to life cycle management. Who you’ll work withWe operate and collaborate closely with colleagues in Development Sciences, which, as a department, is responsible for providing strategy and support in bioanalysis, immunogenicity, safety,



pathology, and regulatory activities. Work with external partners, academic institutions, CROs and consultants as required.What you’ll doDevelop and drive the nonclinical PKPD strategy for projects. Communicating effectively ensuring implementation in projects.Ensure translation from in vitro data and in vivo nonclinical studies to prediction of efficacy and safety in patients. Initiate and engage in multifunctional collaborations to facilitate the advancement of drug candidates and build a thorough knowledge of drug pharmacology and PKPD, leading to quantitative translation to the clinic.Build PKPD models of sufficient complexity to allow hypothesis testing and inform decision-making. Represent the interests of QCP internally and externally in matters relevant to mechanistic PKPD and contribute to enhancing the scientific reputation of Non-Clinical PKPD, QCP and UCB.Provide required support

📌 Principal Scientist PK/PD (España)
🏢 Ucb Group
📍 España