EMBL Grenoble specializes in fundamental research in structural biology, and in developing state-of-the art instrumentation, methods and services. The site is located on the dynamic European Photon and Neutron science campus (EPN campus), together with other international and French research institutions. We are looking for a Research Technician to join Marquez Team in the EMBL Grenoble Unit.

The Marquez team has a strong focus on technology and methods development in macromolecular crystallography and operates the High Throughput Crystallization Laboratory (HTX Lab) at EMBL Grenoble. The HTX lab is one of the largest platforms for automated macromolecular crystallization screening in Europe and is offering advanced crystallography services to users in academia and industry worldwide.

The Marquez

Team has developed automated pipelines for ligand and fragment-based screening by X-ray crystallography based on the CrystalDirect technology for automated crystal harvesting and the CRIMS software. You will cooperate with other team members towards the operation of the HTX facility, further development of our automated crystallography and fragment screening pipelines and will contribute to research projects. Operation of the automated crystallography platform comprising automated liquid handling, imaging and crystal harvesting robotic systems.

Liaising with HTX lab users. Contributing to further development of automated crystallography pipelines for fragment screening based on the CrystalDirect technology and the CRIMS software within the framework of the EC funded projects, including the Fragment Screen project. DNA cloning, protein expression and purification and protein crystallography will be performed as part of the internal research projects.

Management of orders and consumables for the HTX laboratory and general management and maintenance of robotic equipment (arranging with external companies for repairs when necessary). Participation in research projects in cooperation with other members of the team,



including fragment screening on targets of biomedical or biotechnological relevance. A degree in biochemistry (Masters, Bachelor degree or equivalent) or a related field from a technical school or university.

Skills in protein production for structural studies and in protein crystallization as well as the use of robotic laboratory equipment.

Experience in diffraction data collection or fragment screening. Desire to work in an international environment and to contribute to high quality research and services. Fluency in English and good computer skills.

Experience in structural analysis through macromolecular crystallography, ligand screening or the analysis of small molecule-protein interactions.

Contract length: Grade 4 or 5 depending on experience and qualifications (monthly salary starting at €3.395, 47 after tax and before 12,99% EMBL social security deductions) + other paid benefits based on personal circumstances. We encourage applications from individuals who can complement our existing team – we believe that success is built on having teams whose backgrounds and personal experiences reflect the diversity of the populations that our science serves.

Salary free of income tax, Monthly family, child and non-resident allowances, annual salary review, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances Versátil working arrangements Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover) Generous time off: 30 days annual leave per year, in addition to public holidays Relocation package including installation grant (if applicable) Free shuttle bus (Heidelberg), library, subsidised on-site cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely) Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance. We recruit internationally and successful candidates are offered visa exemptions. Find out how we apply DORA principles to our recruitment and performance assessment processes here.

📌 Technician / Research Technician (Cataluña)
🏢 European Molecular Biology Laboratory
📍 Cataluña