The opportunity:
Join Sanofi's Biologics AI & Design team at the forefront of a revolution in drug discovery. We're building next-generation foundational models that are directly shaping our therapeutic pipeline — designing antibody and NANOBODY® molecules that will become tomorrow's medicines for patients worldwide.
What makes this role unique:
- Proprietary biological data at scale — Access to one of the world's largest proprietary datasets of antibody sequences, structures, and functional annotations from decades of therapeutic development
- World-class compute infrastructure — State-of-the-art GPU clusters and cloud resources for training large-scale foundational models
- Real therapeutic impact — Your models will be validated against real targets and integrated into live drug discovery programs
- Scientific freedom — We encourage publication, conference participation, and collaboration with leading academic labs
- Integral collaboration — Work with interdisciplinary teams across computational biology, protein engineering, and therapeutic development
What You'll Do
Build the future of protein therapeutics design:
- Architect and train next-generation foundational models for antibody and NANOBODY® design, including protein language models, structure prediction models, diffusion-based generative models, and multimodal architectures
- Push the boundaries of generative protein design — develop novel training strategies, fine-tuning approaches, and inference methods that leverage Sanofi's unique biological data assets
- Validate rigorously — design benchmarking strategies and work with wet-lab teams to experimentally validate model predictions on therapeutically relevant targets
- Collaborate across disciplines — partner with antibody engineers, structural biologists, screening teams, and therapeutic area experts to understand biological constraints and opportunities
- Stay at the cutting edge — monitor emerging architectures and methods, evaluate t
📌 Principal Machine Learning Scientist for Protein Design (Barcelona)
🏢 Sanofi
📍 Barcelona
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