VHIR offers vacant position for a Bioinformatics – AI
Technician in Clinical and Translational Bioinformatics Research
Group Education and qualifications: Required: Medical degree or
equivalent academic background in Health Sciences Currently
enrolled in a PhD program in Biomedicine or a closely related field
Fluency in English (business level) Experience and knowledge:
Required: A minimum of two years of experience in the development
of ML/AI models for continuous variable prediction Knowledge of MLR
and XGBoost regression models (Implementation and interpretation)
Demonstrated experience developing and using ensemble models
(different kinds of jury averaging) Good coding skills in Python
Experience processing (normalisation and filtering) DMS datasets
Proven knowledge of AlphaFold models Experience in feature
engineering Desired: Knowledge of statistics, including density
modelling skills Advanced use of Generative AI tools Main
responsibilities and duties: The selected candidate will be
responsible for advancing and further developing the group’s




artificial intelligence models for predicting the functional impact
of missense variants. These models were originally developed within
the group and have achieved international recognition, including
first-place rankings in the CAGI 7 international challenge focused
on functional impact prediction of missense variants. The role
therefore entails a high level of responsibility, requiring the
candidate to extend and enhance an established, state-of-the-art
modelling framework. The models primarily produce continuous
predictions, although classification approaches may also be
employed, and are integrated using ensemble methodologies. The
framework combines multiple modelling techniques, including
Multiple Linear Regression (MLR) and gradient boosting algorithms
such as XGBoost, together with feature engineering strategies based
on probabilistic, typically Bayesian, models. Preparation of the
data for publication process La

📌 Bioinformatics – AI Technician (Cataluña)
🏢 VHIR
📍 Cataluña