The Pneumology Research Group at Vall d’Hebron
Institute of Research is seeking a highly motivated Graduated
Technician to join its Lung Transplantation Program. The
multidisciplinary team is composed of clinicians and scientists
whose main objective is to improve long-term survival of lung
transplant patients through cutting-edge translational research.
The selected candidate will work on the DEFIBER IV project: “Final
preclinical steps for the development of new molecules for the
treatment of fibrotic diseases” within the Public-Private
Collaboration Projects Call 2024 consortium. In particular the
candidate will work in Ex vivo characterisation of the effect of
GTX-11m on Interstitial Lung Diseases (ILDs) , focused on the
development and application of human precision-cut lung slices
(hPCLS) as an ex vivo translational model to evaluate novel
anti-fibrotic therapies. The candidate will work in a
multidisciplinary environment involving translational pulmonary
research, molecular biology, and human tissue-based experimental
models. Main responsibilities and duties:
Support the execution of
the DEFIBER IV project focused on the preclinical evaluation of
novel anti-fibrotic therapies using human lung tissue models.
Create, maintain, and update study databases containing clinical,
experimental, and laboratory data. Process, register, store, and
manage human biological samples following laboratory and biobank
procedures. Prepare, culture, maintain, and cryopreserve human
precision-cut lung slices (hPCLS) derived from fibrotic and
non-fibrotic lung tissue. Perform ex vivo experimental assays in
hPCLS under fibrotic and pharmacological stimulation conditions.
Conduct molecular and cellular biology techniques including RNA
extraction, RT-qPCR, ELISA, immunofluorescence,
immunohistochemistry, and histological staining. Perform quality
control procedures and assist in data analysis and interpretation
of experimental results. Assist in tissue imaging and
microscopy-based ana
📌 Graduated Technician (Cataluña)
🏢 VHIR
📍 Cataluña