Experteer Overview
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As a Pharmacokinetics/Translational Modeling Specialist, you will develop and qualify PBPK models to support clinical drug development and regulatory submissions. You will collaborate with DMPK and Clinical Pharmacology teams to translate in vitro, preclinical, and clinical data into actionable development decisions. This role offers opportunities to contribute to broader CPQP initiatives and stay at the forefront of modeling science and regulatory expectations. You will work in a fast-paced, cross-functional environment to drive informed decisions across therapy areas.
Compensaciones / Ventajas
• Develop and qualify mechanistic PBPK models for internal decisions and regulatory use
• Apply PBPK to predict DDIs, pediatric populations, and other clinical development questions
• Collaborate with DMPK and Clinical Pharmacology scientists to build and refine models




• Produce submission-ready analyses and regulatory documentation with clear communication
• Keep abreast of literature, modeling advances, and regulatory expectations
• Utilize PBPK platforms (Simcyp, GastroPlus, PK-Sim) and script in R/Python for analysis and automation
Responsabilidades
• PhD preferred or equivalent (MSc/Pharm.D)
• Experience with PBPK platforms (Simcyp, GastroPlus, PK-Sim)
• Scripting in R and/or Python for data xqbhyrx analysis and workflow automation
• Familiarity with AI-enabled workflows in compliant research environments
• 1–4 years of drug development experience with emphasis on PBPK
• Strong knowledge of PK, DDIs, regulatory guidance, and modeling and simulation
• Ability to lead PBPK activities at project level
• Excellent oral and written communication; regulatory documentation experience
• Fluency in English
Requisitos principales
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📌 Senior Clinical PBPK Modeling Scientist (Barcelona)
🏢 AstraZeneca
📍 Barcelona