Bioinformatician at Cellular & Systems Neurobiology groupThe InstituteThe Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a adaptable and efficient administration and by high-end and innovative technologies.We are looking for a Bioinformatician at the Cellular and Systems Neurobiology lab to work on the project titled “Understanding interneuronopathy in Down syndrome to identify interneuron targeted therapy (INTO-DS) (Agencia Estatal de Investigación (PID OB-I00) and led by Dr Mara Dierssen and led by Dr Mara Dierssen.The position requires a candidate with previous experience in Bioinformatics. The candidate will process and analyse multi-omics datasets (eg. snRNA-Seq, snATAC-Seq, spatial transcriptomics). The candidate will design and apply integrative data analysis (computational/statistical/causal) and visualization techniques for multi-omic data to address research hypotheses. The candidate will apply machine learning models to clinical and omics data for classification tasks. We are looking for highly motivated and organized candidates with good communication skills, capable of working in a group but also with a high degree of work autonomy.About the labThe Dierssen lab is centred on understanding cognition and behaviour and their perturbation in intellectual disability. We are an interdisciplinary team of physicists,



bioinformaticians and experimental biologists, and we focus on data collection (behaviour, 3D imaging, genomic data) of many variables of the system (longitudinal behavioural analysis, population-based analysis in neuronal networks, gene expression patterns). We take advantage of computer modelling and bioinformatics analysis (gene networks, neuronal network modelling, etc.) to tackling classical unresolved questions in the field.Whom would we like to hire?Professional experienceMust HaveYou have at least 2 years of experience as bioinformatician in an area involving NeuroscienceYou have proven experience in big data analysis (RNASeq, snRNA-Seq, snATAC-Seq, spatial transcriptomics)You have excellent understanding of transcriptomic and epigenomics workflows, data structure and potential data analysis approaches to efficiently integrate and/or develop analysis and visualization protocolsYou have experience in analyzing, integrating and harmonizing multi-omics datasets e.g., using network-based, graph modelling,



dimensionality reduction or machine learning approachesYou can process and derive novel insights from integrative analysis of multi-omic datasetsDesirable but not required/ Nice to havePrevious experience in neuropsychiatric research will be an added valueEducation and trainingYou hold a PhD in Neuroscience, Bioinformatics, Genomics, Data Science, or related fields.LanguagesGood spoken and written EnglishTechnical skillsYou have proficiency in R or Python for data analysis and programmingSolid knowledge of UNIX-like operating systems and shell scriptingYou have knowledge in advanced statistics and machine learningCompetencesHighly developed organizational skillsA highly motivated and organized candidate, capable of working in a group, and with a high degree of work autonomyThe Offer – Working ConditionsContract duration: Technical and scientific activities contract linked to the project duration (estimated until 28/02/2027).Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.
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📌 Bioinformatician at Cellular & Systems Neurobiology group (Barcelona)
🏢 Centre For Genomic Regulation
📍 Barcelona