Company Description:

Amadix is a molecular diagnostics company specializing in liquid biopsy tests for early cancer detection. The company focuses on developing innovative and disruptive technologies that can identify cancer years before symptoms appear. Amadix is driven by a mission to extend people’s lives by enabling earlier and more accurate diagnosis. Team members collaborate in a science-driven, fast-paced environment that bridges cutting-edge research and clinical application.

Joining

Amadix offers the opportunity to contribute directly to advancing cancer diagnostics and patient outcomes.

Role Description:

We are looking for an experienced scientific leader to define and drive our company's biomarker strategy in oncology, bridging cutting-edge science with real-world diagnostic applications.

This is a unique opportunity for someone passionate about translating biomarker discoveries into clinically validated diagnostic solutions that improve patient outcomes.

The successful candidate will lead the biomarker development journey—from biomarker discovery and analytical validation to the development of proprietary diagnostic assays,

regulatory approval and their implementation in clinical practice.

This role combines strategic leadership with a strong hands-on approach. You will work across R&D;, Clinical Development, Regulatory Affairs, Quality and Business teams, ensuring that scientific discoveries are successfully transformed into robust, clinically meaningful diagnostic products.

Key responsabilities:

- Biomarker Strategy: Define and lead biomarker strategies from identification and validation to clinical implementation.
- Assay & Diagnostic Development: Lead the development, optimization and validation of biomarker-based assays and diagnostic platforms.
- Clinical & Analytical Validation: Oversee analytical and clinical studies supporting regulatory approval and clinical implementation.




- Scientific & Data Leadership: Guide biomarker research, data analysis and interpretation in collaboration with bioinformatics and biostatistics teams.
- Cross-functional Leadership: Lead multidisciplinary projects across R&D;, Clinical, Regulatory, Quality and Business teams.
- External Collaboration: Build strategic partnerships with academic, clinical, technology and industry stakeholders.

We are looking for a senior professional with:

- 10+ years of experience in biomarker development
- Extensive experience in translational oncology and biomarker discovery, validation and translational diagnostics
- Deep expertise in oncology biomarkers, particularly: miRNA and protein biomarkers
- Proven experience in diagnostic/IVD assay development, analytical validation and clinical implementation
- Experience translating biomarkers into clinically validated diagnostic products
- Strong hands-on experience and in-depth technical knowledge of routine molecular biology and protein analysis techniques, including RT-qPCR, qPCR, Digital PCR (preferred), ELISA, Immunoassays, Multiplex.
- Extensive experience with analytical platforms , including: Luminex® technology, QuantStudio™ Real-Time PCR System (or similar) and KingFisher™ Nucleic acid extraction platforms
- Proven expertise in the development, optimization and validation of analytical assays, reagents and laboratory workflows for biomarker-based diagnostic applications.




- Experience interpreting biomarker data and translating scientific evidence into clinically meaningful diagnostic solutions.
- Working knowledge of statistical analysis and bioinformatics tools applied to biomarker
- Strong analytical and strategic skills , with the ability to interpret complex data and support biomarker strategy, portfolio prioritization and resource allocation
- Proven experience leading cross-functional scientific programs across clinical, regulatory, commercial and technical teams
- Strong leadership and communication skills , including team management, mentoring and the ability to communicate complex scientific concepts to diverse stakeholders
- Experience collaborating with external partners , including academic institutions, clinical investigators and industry stakeholders

Preferred experience:

- Experience with liquid biopsy, proteomics, NGS-based biomarker discovery or Companion Diagnostics (CDx)
- Knowledge of ISO 13485, IVDR and Design Control principles

Background education:

- PhD in Molecular Biology, Oncology, Biotechnology, Biomedical Sciences or a related scientific discipline is strongly preferred.
- Master's or Bachelor's degree in Life Sciences with extensive relevant experience will also be considered.

This is an opportunity to work at the intersection of biomarker science, diagnostics and precision oncology , helping translate scientific innovation into solutions with the potential to improve patient care.

What We Offer:

- A competitive salary commensurate with experience.
- A full-time, permanent contract.
- Versátil working arrangements, including hybrid working options.
- Continuous learning and professional development opportunities.
- A collaborative, international, and innovative working environment.
- The opportunity to contribute to groundbreaking advancements in precision oncology and biotechnology.

Location : Madrid Contact : [email protected]

📌 Head of Biomarker Strategy & Translational Diagnostics (Madrid)
🏢 Amadix
📍 Madrid