Postdoc position - Microbiome Signatures of Heavy Menstrual Bleeding

CBGP (UPM-INIA/CSIC), Madrid, Spain Hybrid (partial remote) Start expected before December 2026 1.5–2 years (depending on start date) ≈ €41,000 gross / year Apply by 1 September 2026 (or until filled)

The Comparative Genomics & Metagenomics Lab (CGMLab, https://cgmlab.org) at the Centre for Plant Biotechnology and Genomics (CBGP, Madrid) is seeking a postdoctoral researcher to join the microbiome component of the "Missed Vital Sign" (MVS) project.

About The Project

MVS is funded by the Wellcome Leap 'The Missed Vital Sign' programme, which is a 36-month collaborative initiative that is transforming the study and diagnosis of female reproductive health. The project uses vaginal and menstrual fluid as a non-invasive biological proxy to study heavy menstrual bleeding (HMB), a condition that affects over 30% of women of reproductive age but remains under-researched because traditional diagnostics rely on invasive biopsies or blood tests. Our multidisciplinary team, comprising experts in reproductive biology,



generative AI, clinical gynaecology, and microbiome science, collects samples from 500 women using smart menstrual cups with integrated biosensors. We integrate single-cell RNA sequencing, spatial transcriptomics, genotyping, and microbial profiling with AI to identify the causal factors of HMB, stratify patients, and validate therapeutic targets in patient-derived endometrial organoids.

Our lab is leading the microbiome component, which involves understanding how microbial communities in the female reproductive tract correlate with host endometrial cells and contribute to HMB. However, menstrual-fluid microbiome analysis presents challenges due to low microbial biomass and an overwhelming presence of human host DNA. To overcome this, we combine regular shotgun sequencing with targeted metagenomic capture sequencing technology to achieve high precision, sensitivity, and phylogenetic resolution

📌 Postdoc position – Microbiome Signatures of Heavy Menstrual Bleeding (Madrid)
🏢 Sebibc
📍 Madrid