The Barcelona Institute for General Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education. ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level. Research is organized in five programs: Climate, Air Pollution, Nature and Urban Health; Environment and Health over the Lifecourse; Global Viral and Bacterial Infections; Malaria and Neglected Parasitic Diseases and Maternal Child and Reproductive Health. ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.

WHAT WE ARE LOOKING FOR:
Control of soil transmitted helminths (STH) and Schistosomiasis (SCH) has been part of routine programmes for many years, yet, the efficacy and effectiveness of these programmes is challenged by low and failing drug efficacy and growing concerns of anthelmintic resistance,



calling for a revision of the MDA-drug strategies. In this regard, the novel fixed-dose co-formulation (FDC) including albendazole and ivermectin has proven to be safe and to overcome most of the challenges in drug efficacy for STH. For T. solium the situation is very different from STH and SCH as currently there are no countries routinely implementing control. 3SI-CONTROL will assess the safety and cost-effectiveness of the FDC co-administration with praziquantel in reducing the prevalence of T. solium, STH and SCH, in a randomised controlled trial embedded in solid implementation research. Results from 3SI-CONTROL will thereby provide a scientific evidence base on the safety and effectiveness of integration of T. solium control with STH and SCH, considering the One Health approach. Beyond this, the substantial implementation research component will enable bridging the gap between the evidence-based pract

📌 Project Manager (Barcelona)
🏢 Barcelona Institute for Global Health (ISGlobal)
📍 Barcelona