17 ago
|
Fundació TIC Salut i Social
|
Barcelona
17 ago
Fundació TIC Salut i Social
Barcelona
Organisation/Company Fundació Hospital Universitari Vall d'Hebron- Institut de recerca Department Research Department Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions Ph D Positions Application Deadline 22 Jul *********:59 (Europe/Andorra) Country Spain Type of Contract Temporary Job Status Full-time Hours Per Week 37.5h/week Is the job funded through the EU Research Framework Programme?
Other EU programme Is the Job related to staff position within a Research Infrastructure?
NoOffer DescriptionThe earth's daily rotation causes profound, yet repetitive, changes to environmental conditions.
In response, species from prokaryotes to humans have evolved circadian clocks to drive anticipatory daily rhythms in biological processes ranging in magnitude from DNA replication to sleep-wake cycles.
However, cellular, tissue and systemic circadian rhythms exhibit a generalised decay during the ageing process that may contribute to the development of aged-related diseases and onset of frailty.
In theCircadian Rhythms and Ageing laboratory, we aim to determine why this detrimental decay occurs and ask how we can correct or exploit these changes.
To do so, we apply cutting edge in vivo, in vitro and in silico tools to provide unique, clinically relevant perspectives on the ageing of the bodies circadian system.Age is cancers primary risk factor and a significant determinant of how this often-devastating disease presents and progresses.
Concurrently, circadian inputs from the body are known to drive daily rhythms in tumour microenvironment composition, metastasis seeding and treatment response, whilst disruption of physiological circadian rhythms is itself an established tumour promoter.
However, whether the ageing of the bodies circadian system reshapes the initiation and development of cancer remains unknown.
To address this question, the selected candidates develop a European Research Council-funded project t
📌 First Stage (Barcelona)
🏢 Fundació TIC Salut i Social
📍 Barcelona