The idóneo candidate will have strong background in pharmacokinetics and translational modeling.
Se pueden requerir diversas habilidades interpersonales y experiencia para el siguiente puesto. Por favor, asegúrese de consultar la descripción a continuación con atención.
You will participate in implementing innovative and quantitative approaches to advance clinical drug development.
Developing, qualifying, and applying mechanistic PBPK models using in vitro, preclinical, clinical, and literature data to support clinical development decisions across therapy areas.
In addition, you will have opportunities to contribute to broader areas within Clinical Pharmacology & Quantitative Pharmacology (CPQP) as per your experience, interests, and expertise dictate.
Typical Accountabilities Utilize physiologically-based pharmacokinetic (PBPK) and translational modeling tools to enable clinical PK projections for drug-drug interactions (DDIs), pediatric and other specific populations, and other clinical development questions Collaborate with Drug Metabolism and Pharmacokinetic (DMPK)



Scientists and Clinical Pharmacology scientists to generate these mechanistic models Develop fit-for-purpose, qualified PBPK models suitable for internal decision-making and regulatory use, including support for submission documentation and health authority interactions.
Communicate clearly and effectively both internally and externally on topics related to PBPK clinical DDI and pediatric and other specific populations predictions Keep up to date with emerging literature, modeling science, and regulatory expectations Education, Qualifications, Skills and Experience EssentialPhD degree preferred or equivalent (M.Sc./Pharm.D.) Experience using PBPK platforms such as Simcyp, GastroPlus, or PK-Sim, together with scripting in R and/or Python for data analysis, visualization, and workflow automation.
Familiarity with AI-enabled scientific workflows, such as literature mining, coding assistance, or document s

📌 Senior Clinical PBPK Modeling Scientist (Barcelona)
🏢 AstraZeneca
📍 Barcelona