Principal Clinical Scientist (AI Training) About The Role What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands and reasons about clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research — ensuring the clinical data powering next-generation AI systems meets the standards expected in real-world regulatory submissions. This is a fully remote, flexible contract role designed for experienced clinical scientists who want to work at the frontier of AI and biomedical research.

No AI background required — just deep clinical expertise and a sharp eye for scientific quality.

Organization: Alignerr

Type: Hourly Contract

Location: Remote

Commitment: 10–40 hours/week What You'll Do Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training and evaluation

Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards

Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance

Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and methodology





Work independently and asynchronously — fully on your own schedule Who You Are Senior-level experience designing clinical trial protocols for regulatory submission (FDA, EMA, or equivalent)

Deep expertise interpreting clinical data within regulatory frameworks

Strong foundation in clinical research methodology, biostatistics, or translational science

Naturally detail-oriented with high standards for scientific accuracy and consistency

Clear and effective written communicator able to document feedback in structured formats Nice to Have Prior experience with data annotation, data quality review, or AI evaluation workflows

Background in pharmacology, epidemiology, or outcomes research

Familiarity with AI tools or clinical decision-support systems

Experience working across multiple therapeutic areas or trial phases Why Join Us Work directly on frontier AI systems shaping the future of clinical and biomedical research

Influence how AI understands, evaluates, and reasons about real-world clinical evidence

Fully remote and adaptable — work when and where it suits you

Freelance autonomy with the structure of meaningful, expert-level work

Collaborate with leading AI research labs and teams pushing the boundaries of medical AI

Potential for ongoing work and contract extension as new projects launch

📌 Principal Clinical Scientist (Madrid)
🏢 Alignerr
📍 Madrid