The Institute
The Institute
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a adaptable and efficient administration and by high-end innovative technologies.
The role
The Höpfler lab is looking for a postdoctoral researcher to lead a project in the field of RNA biology and gene regulation with a strong interest in driving development of sequencing methods to identify mRNA decay substrates and decipher degradation mechanisms.
The successful candidate will join the Dynamics of Protein Synthesis and RNA Decay Group. Their work will address an exciting question in gene regulation: how cells dynamically control the stability of messenger RNAs by selective degradation during protein synthesis by the ribosome. The lab studies this problem in the context of both fundamental molecular mechanisms and disease‑related regulation.




The position will be a chance to join a young, ambitious and curiosity‑driven lab at the CRG, one of Europe’s prime institutes for molecular life sciences, surrounded by the dynamic Barcelona research environment. The project is embedded in the ERC‑funded DECODE‑PMD project to better understand peptide‑mediated mRNA decay (PMD).
Key responsibilities include:
- Development of sequencing approaches to identify PMD substrates
- Bioinformatic data analysis and visualization
- Identification and mechanistic characterization of PMD candidate substrates
- Presentation of data at international conferences and manuscript preparation
- Leading and managing international collaborations
- Active participation in lab meetings and contribution to a culture of technical excellence and scientific curiosity

Whom would we like to hire?
We are particularly interested in candidates with a hybrid wet lab + bioinformatics background w

📌 Postdoc in the Dynamics of Protein Synthesis and RNA Decay Lab (España)
🏢 Centre For Genomic Regulation
📍 España