TakeTalent joins PharmaMar in the search for a Clinical Pharmacology Scientist to support the development of innovative oncology therapies through cutting-edge clinical pharmacology and model-informed drug development strategies.

At PharmaMar, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.

What will you do?

• Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy.
• Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team.
• Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders.
• Perform pharmacokinetic analyses,



including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling.
• Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships.
• Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.
• Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.
• Develop and maintain high-quality analytical workflows and databases following Good Coding Practices.
• Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports.
• Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA.
• Collaborate closely with cross-funct

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 BUSINESS SOLUTIONS by TakeTalent
📍 Madrid