What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands and reasons about clinical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research — ensuring the clinical data powering next-generation AI systems meets the standards expected in real-world regulatory submissions.
This is a fully remote, adaptable contract role designed for experienced clinical scientists who want to work at the frontier of AI and biomedical research. No AI background required — just deep clinical expertise and a sharp eye for scientific quality.
Design and review clinical trial protocols used to generate high-quality, regulatory-grade datasets for AI training and evaluation
Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
Provide expert, structured feedback that helps AI models reason more accurately about clinical trial data, outcomes, and methodology
Work independently and asynchronously — fully on your own schedule
Who You Are
Senior-level experience designing clinical trial protocols for regulatory submission (FDA, EMA, or equivalent)
Deep expertise interpreting clinical data within regulatory frameworks
Strong foundation in clinical research methodology, biostatistics, or translational science
Naturally detail-oriented with high standards for scientific accuracy and consistency
Clear and effective written communicator able to document feedback in structured formats
Nice to Have
Prior experience with data annotation, data quality review, or AI evaluation workflows
Background in pharmacology, epidemiology, or outcomes research
Familiarity with
📌 Principal Clinical Scientist (Madrid)
🏢 Alignerr
📍 Madrid
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