TakeTalent joins PharmaMar in the search for a Clinical Pharmacology Scientist to support the development of innovative oncology therapies through cutting-edge clinical pharmacology and model-informed drug development strategies. At PharmaMar, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making. What will you do? • Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy. • Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team. • Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders. • Perform pharmacokinetic analyses,



including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling. • Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships. • Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses. • Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results. • Develop and maintain high-quality analytical workflows and databases following Good Coding Practices. • Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports. • Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA. • Collaborate closely with cross-function

📌 Clinical Pharmacology Principal Scientist (Leganés)
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📍 Leganés