TakeTalent joins PharmaMar i in the search for a Clinical Pharmacology Scientist to support the development of innovative oncology therapies through cutting-edge clinical pharmacology and model-informed drug development strategies.At PharmaMar, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.What will you do?Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy.Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team.Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders.Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA),
Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling.Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships.Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.Develop and maintain high-quality analytical workflows and databases following Good Coding Practices.Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports.Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA.Collaborate closely with cross-functional teams including Medical Oncolo