You will join a DMPK drug discovery team in Spain to influence how we translate science into safer, more effective medicines. You will design and deliver modelling and simulation strategies to support discovery and early development projects. You will work closely with project teams across disciplines and locations to inform dose decisions, drug-drug interaction risk, and human pharmacokinetics. We value collaborative thinkers who communicate clearly, mentor others, and apply modelling with scientific rigour and practical judgement. This role is part of GSK's Integral Health Medicines R&D; team which aims to positively impact infectious diseases such as Malaria, Tuberculosis, and AMR that disproportionally impact lower income countries.
Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
Lead development and application of pharmacokinetic and pharmacokinetic-pharmacodynamic (PK/PD) models for small molecules and other modalities to inform project decisions.




Design and deliver translational modelling strategies, including dose prediction and human exposure projections.
Assess and quantify drug-drug interaction (DDI) risk using in vitro-in vivo translation and modelling approaches.
Communicate model assumptions, results and uncertainty clearly to cross-functional teams and governance bodies.
Mentor and coach colleagues on modelling methods, good practices and scientific interpretation.
Contribute to regulatory and internal documents with clear, evidence-based modelling narratives.
Qualifications/Skills

Basic Qualifications:

Degree in Pharmacology, Pharmaceutics, Pharmacokinetics, Mathematics, Bioengineering, or a related discipline.
Practical experience in population PK, PBPK, or mechanistic PK/PD modelling in a biopharma setting.
Hands-on experience with modelling software such as, Matlab (symbiology), Monolix, Simcyp, GastroPlus, or equivalent.
Experience tr

📌 GS DMPK Modeller (Madrid)
🏢 Tamarind Intelligence
📍 Madrid