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Job Title Modelling Team Lead

Salary €45k-€55k + Equity

Company Description Cultzyme is a deep-tech biotech based in San Sebastián building the BION platform—intelligent bioreactors that turn opaque biological processes into programmable systems for the world's most important pharmaceutical manufacturing lines.

You will lead the modeling and intelligence layer at Cultzyme, building the digital twins that optimize biopharmaceutical production. By coupling mechanistic kinetics with data-driven components like neural ODEs and PINNs, you’ll solve the predictability crisis in fermentation, directly impacting how life-saving therapies are manufactured and scaled globally.

Location San Sebastián, Spain (Remote)

Why this role is remarkable

- Impact: Your models will move beyond research papers into the presente manufacturing lines of the world's leading pharmaceutical companies.
- Innovation: Work at the bleeding edge of hybrid modeling, combining first-principles physics with universal differential equations and Bayesian optimization.
- Ownership: As a core member of a high-talent 15-person team, you’ll have the autonomy to define the intelligence trajectory of the entire company.

What You Will Do

- Build hybrid cell growth models using neural ODEs, PINNs, and mechanistic kinetics to create high-fidelity digital twins of bioreactors.
- Design and execute DOE campaigns and Bayesian optimization loops to bridge the gap between intracellular metabolism and 2000L fluid dynamics.
- Develop real-time MLOps pipelines and PAT strategies to enable predictive control and automated process monitoring in regulated environments.





The ideal candidate

- Holds a PhD in Mathematics, Physics, or Statistics with 5+ years of experience applying complex mathematical modeling to engineering problems.
- Deep expertise in hybrid mechanistic/data-driven modeling (ODE/DAE systems) and production-grade Python using libraries like PyTorch or JAX.
- Proven track record of building digital twins and closing the experimental loop with Bayesian optimization and Gaussian process surrogates.

Who are Jack & Jill? Ok, I'll go first. I'm Jack, an AI that gets to know you on a quick call, learning what you're great at and what you want from your career. Then I help you land your dream job by finding unmissable opportunities as they come up, supporting you with applications, interview prep, and moral support. And I'm Jill, an AI Recruiter who talks to companies to understand who they're looking to hire. Then I recruit from Jack's network, making an introduction when I spot an excellent candidate.

How does this work?

- Jack's an AI agent for job searching and career coaching. He works for you.
- Jill is the AI recruiter working for the company. She recruits from Jack's network.
- If it's a match and the company wants to meet you, they'll make the intro. In the meantime, if you'd like, Jack will send you excellent alternatives.

We never post fake jobs This isn't a trick. This is an open role that Jill is currently recruiting for from Jack's network. Sometimes Jill's clients ask her to anonymize their jobs when she advertises them, which means she can't share all the details in the .

We appreciate this can make them look a bit suspect, but there isn't much we can do about it.

Give Jack a spin! You could land this role. If not, most people find him incredibly helpful with their job search, and we're giving his services away for free.

📌 Modelling Team Lead ( + Equity) at Cultzyme (San Sebastián)
🏢 Jack u0026 Jill
📍 San Sebastián