VP Clinical Development — Autoimmunity | Clinical-stage biotech, RemoteLooking for a VP Clinical Development to lead the clinical strategy and design of an autoimmunity / immunology programme moving through early and mid-stage development.Rheumatology, UC and Auto-immunity has seen a huge new wave of interest and investment. The coming together of technologies such as CART, Immuno-Oncology and increased life expectancies has seen new investment, approaches and trials.My client is currently one such company - recent pharma investment, multiple clinical trials and now testing their platform in Autoimmune diseases. So, if you are passionate about auto-immunity clinical trial design and want to help a biotech who are growing into a new area -please keep reading!About the opportunityA well-funded, clinical-stage biotech with a differentiated immuno-modulatory approach in autoimmune / inflammatory disease. Strong science, clean data to date, and a lean team where senior people have real influence over direction. This is a build role at an inflection point, not a maintenance one.Role responsibilitiesOwn clinical development strategy for the autoimmunity programme: indication selection, development pathway, and the design of the trials that de-risk it.Lead protocol design, endpoint strategy, and the scientific rationale underpinning study concepts through to full protocols.Translate emerging clinical and translational data into decisions on future development plans and portfolio direction.Provide the medical and scientific lead on trial execution, including oversight of study conduct, data interpretation, and safety.Contribute to and review key regulatory and clinical documentation (development plans, briefing documents, IND/IMPD-type submissions, investigator brochures).Partner across translational research, regulatory, medical affairs, and operations to keep clinical strategy aligned and moving.Build and manage a small team, with a plan to add one to two hires (permanent or consulting)



as the data and strategy dictate.RequirementsMD required - or Ph.D if previous Rheumatology Trial Design experienceClinical development experience in autoimmunity (Rheuma ideally but any auto-immune with a TCell mediated treatment is relevant).Track record designing Phase I–III trials and shaping development plans.Comfortable operating hands-on in a lean biotech: strategic when needed, in the detail when needed.Based in the EU, able to travel to the German HQ around 4–5 days per month (relocation to Germany welcome but not required).Right vs WrongThis is perfect for - people who are Senior Director / VP already. They want flexibility in their work and like the idea of helping a company enter the next stages of growth. Unafraid to drive projects themselves and enjoy working with smaller teams / get sh*t done mentality.Not right for - people looking for CMO titles or 1-2 days a week. People with no trial design / strategy experience or never touched an autoimmune / rheuma trial. People who want 10 Programmes with 2x people in each trial (that is big pharma, not biotech).Could be right for - maybe open to very experienced consultants who are willing to work 3-4 days a week. You will need strong Auto-immune or Rheuma for this.Could be right for - board certified rheumatologist looking to get into the industry.Open on the exact experience mix — if you're strong on autoimmunity clinical development but lighter on one dimension, or coming from an adjacent immune-mediated indication, it's still worth a sharing your CV.The offer€150,000 – €220,000 base salary, depending on experience.Hybrid: home based within the EU, with ~4–5 days per month at the German HQ (a major German city).A genuine leadership seat: you shape the programme and the team, working directly with the executives - reporting into C Suite. (CEO, CMO, CSO)Join at a pivotal, data-rich moment with room to grow the role as the pipeline advances.Small, supportive, science-driven team. An environment that's genuinely supportive of young families.#J-18808-Ljbffr

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