Offer Description

The Josep Carreras Leukaemia Research Institute (IJC) is a comprehensive cancer research center dedicated to conduct research and drive innovation in the epidemiological, preventive, clinical, translational, and basic aspects of leukaemia and other hematologic malignancies, with the final aim of finding a cure for these diseases. It was created in 2010, and since then has experienced an exponential growth.

The IJC is also part of the network of Excellence Research Centers of Catalonia (CERCA) and was accredited as a Severo Ochoa Center of Excellence by the Ministry of Science, Innovation, and Universities in 2024. Since 2018, the Institute has also been accredited by the Scientific Foundation of the Spanish Association Against Cancer (FCAECC) . Additionally, IJC is one of the centers integrated into the Institut de Recerca Germans Trias i Pujol (IGTP) accreditation as Accredited Health Research Institute (IIS) by the Carlos III Health Institute (ISCIII) .

The IJC's main headquarters is located within the Can Ruti Biomedical Campus, alongside other leading biomedical institutions, providing direct access to cutting‑edge scientific and technological facilities, as well as complementary community services. The IJC has six locations integrated into reference hospitals : Hospital Germans Trias i Pujol, Hospital Clínic, Hospital Sant Pau, Hospital Josep Trueta, Hospital del Mar and Hospital San Joan de Déu. This facilitates close collaboration between basic and clinical researchers,



fostering translational research that integrates basic science with clinical practice in clinical settings.

We are looking for a Research Assistant in Training in the Nuclear architecture in leukemia group led by Dr. Gregoire Stik.

Research Description

The main goal of our lab is to uncover novel biomolecular mechanisms driving the development of B-cell acute lymphoblastic leukemia. We are specially focusing on understanding the role of oncogenic fusion proteins induced by chromosomal translocations on chromatin organization, gene expression and how eventually they participate in disease progression.

The project aims to unravel the molecular mechanisms that regulate the function of fusion oncoproteins by integrating multiple experimental and computational approaches, including state‑of‑the‑art technologies such as genome editing, optogenetics, high‑resolution microscopy, and chromatin conformation capture.

Understanding how translocation can affect biochemical properties of protein will offer potential new biomedical applications for the treatment of haematological malignancies.

Main Responsibilities

- Design and construct various mutant forms of a target oncogene using molecular cloning techniques.




- Conduct functional assays to evaluate the biological activity of oncogene mutants in appropriate cellular models.
- Maintain accurate experimental records and analyze data to assess the impact of specific mutations.
- Collaborate with other lab members to optimize experimental protocols and interpret results.

Qualifications

- Master’s degree in biomedical sciences or similar.
- Previous experience in a research laboratory.
- High level of communication skills and teamwork abilities.
- Strong background in cellular and molecular biology; additional expertise in epigenetics is an advantage.
- Proficiency in English (spoken and written).
- Organised, independent, proactive, self‑motivated, and enthusiastic.
- Language: English – Excellent level.

Contract and Conditions

- Temporary position: 1 year (training contract) with possibility to continue as PhD candidate.
- Full‑time contract of 39 hours per week.
- Measures to reconcile work and family life: versátil work schedule, working days of vacation and days for personal matters.
- Flexible remuneration programme (kindergarten and other measures).
- An exciting and innovative research project.
- Working in the mixed basic and clinical research environment of the Josep Carreras Leukaemia Research Institute.
- Incorporation in a multinational and highly collaborative team.
- The stimulating environment of the Barcelona metropolitan area.

Application Deadline

Please submit your application by July 30th, 2027.

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📌 VAC_57_2026 - RESEARCH ASSISTANT IN TRAINING (Municipio de Badalona)
🏢 Euraxess
📍 Municipio de Badalona