TakeTalent

joins

PharmaMar i

n the search for a

Clinical Pharmacology Scientist

to support the development of innovative oncology therapies through cutting-edge

clinical pharmacology

and

model-informed drug development strategies

.

At

PharmaMar

, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making.

Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy. • Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team. • Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders. • Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling. • Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships. • Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses. • Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results. • Develop and maintain high-quality analytical workflows and databases following Good Coding Practices. • Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports.



• Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA. • Collaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders. • Participate in departmental initiatives that contribute to the overall success of Early Clinical Development programs.

Bachelor’s degree in

Pharmacy, Medicine, Biology, Biotechnology

or a related scientific discipline. • Master’s degree and PhD in

Pharmacology

, Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field. • Fluent English, both written and spoken. • More than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine. • Strong programming skills in R and SAS for data analysis and process automation. • Knowledge of additional programming languages such as Python and Bash. • Solid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses. • Experience with

Next-Generation Sequencing (NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines. • Competitive annual salary and performance-based bonus. • Comprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others. • Hybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility. • The opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment. • If you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you.

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 BUSINESS SOLUTIONS by TakeTalent
📍 Madrid