06 ago
|
Tamarind Intelligence
|
Colmenar Viejo
06 ago
Tamarind Intelligence
Colmenar Viejo
ppbTakeTalent /b joins bPharmaMar i /b in the search for a bClinical Pharmacology Scientist /b to support the development of innovative oncology therapies through cutting-edge bclinical pharmacology /b and bmodel-informed drug development strategies /b. /ppAt bPharmaMar /b, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making. /ph3What will you do? /h3ulliSupport the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy. /liliProvide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team. /liliCoordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders. /liliPerform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling. /liliConduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships. /liliSupport first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses. /liliContribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results.
/liliDevelop and maintain high-quality analytical workflows and databases following Good Coding Practices. /liliContribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports. /liliProvide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA. /liliCollaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders. /liliParticipate in departmental initiatives that contribute to the overall success of Early Clinical Development programs. /li /ulh3Position requirements /h3ulliBachelor's degree in Pharmacy, Medicine, Biology, Biotechnology or a related scientific discipline. /liliMaster's degree and PhD in Pharmacology, Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field. /liliFluent English, both written and spoken. /liliMore than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine. /liliExperience authoring scientific publications and technical reports. /liliProven expertise in pharmacometric modeling tools such as bNONMEM, Monolix,
PK-Sim or similar platforms /b. /liliStrong programming skills in R and SAS for data analysis and process automation. /liliKnowledge of additional programming languages such as Python and Bash. /liliExperience in bioanalysis and biomarker evaluation. /liliSolid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses. /liliExperience with bNext-Generation Sequencing (NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines /b. /liliExcellent communication skills and the ability to work independently while contributing effectively within multidisciplinary teams. /li /ulh3What do we offer? /h3ulliCompetitive annual salary and performance-based bonus. /liliComprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others. /liliFlexible start time (7:30h to 9:30h) and intensive working hours on Fridays. /liliHybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility. /liliThe opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment. /liliA strong commitment to diversity, equal opportunities and an inclusive work environment where all talent is valued and respected. /li /ulpIf you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you. /p /p #J-18808-Ljbffr
📌 Clinical Pharmacology Principal Scientist (Colmenar Viejo)
🏢 Tamarind Intelligence
📍 Colmenar Viejo