ph3Overview /h3 pThe Höpfler lab at the Institute for Genomic Regulation (CRG) is offering a postdoctoral position focused on RNA biology and gene regulation. The role involves leading a project to develop sequencing methods that identify messenger RNA (mRNA) decay substrates and to decipher the mechanisms of degradation. /p h3Responsibilities /h3 ul liDevelop sequencing approaches to identify peptide-mediated mRNA decay (PMD) substrates /li liPerform bioinformatic data analysis and visualization of sequencing datasets /li liIdentify and mechanistically characterize PMD candidate substrates /li liPresent data at international conferences and prepare manuscripts /li liLead and manage international collaborations /li liActively participate in lab meetings and contribute to a culture of technical excellence and scientific curiosity /li /ul h3Qualifications /h3 pWe are particularly interested in candidates with a hybrid wet‑lab and bioinformatics background who have a track record in RNA biology or gene regulation. /p h3Must Have /h3 ul liBioinformatics experience in the analysis of (RNA) sequencing data /li liExperience with common laboratory techniques in cell and molecular biology /li liPhD degree (or expected to complete the degree before starting) in cell/molecular biology, bioinformatics, or a related field /li liStrong publication record commensurate with career stage /li liAbility to pursue research projects independently /li /ul h3Desirable /h3 ul liExperience with massively parallel reporter assays (MPRAs)



/li liExperience exploring mRNA turnover on a transcriptome‑wide scale /li liBackground in RNA biology, translational control, or related areas /li /ul h3Languages /h3 ul liFluency in written and spoken English /li /ul h3Computer Skills /h3 ul liProficiency with data analysis software (R, Python) /li liExperience using high‑performance computing clusters /li liAdvanced MS Office experience /li /ul h3Competences /h3 ul liCuriosity and critical thinking /li liRigor, organization, and autonomy /li liStrong analytical, interpersonal, and communication skills /li /ul h3Offer – Working Conditions /h3 ul liContract duration: Technical and scientific activities contract (estimated duration 2 years) /li liEstimated annual gross salary: Salary will be commensurate with qualifications and consistent with our pay scales /li liTarget start date: from October 2026 (flexible) /li /ul h3EEO Statement /h3 pWe offer and promote a diverse and inclusive environment and welcome applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity. /p pThe CRG is committed to reconciling work and family life of its employees and offers extended vacation periods and the possibility to benefit from adaptable working hours. /p h3Application Deadline /h3 pThe position will remain open until it is covered. /p h3Contact /h3 pMarkus Höpfler Additional information can be found on the lab website: /p /p #J-18808-Ljbffr

📌 Postdoc in the Dynamics of Protein Synthesis and RNA Decay Lab (Barcelona)
🏢 Somma
📍 Barcelona