pstrongTakeTalent /strongjoins strongPharmaMar i /strongn the search for a strongClinical Pharmacology Scientist /strongto support the development of innovative oncology therapies through cutting-edge strongclinical pharmacology /strongand strongmodel-informed drug development strategies /strong. /ppbr /¿Todo listo para enviar su solicitud? Por favor, lea la descripción al menos una vez antes de hacer clic en "Solicitar".br / /ppAt strongPharmaMar /strong, they are committed to advancing science and transforming patient outcomes through innovative oncology research. The Clinical Pharmacology team plays a critical role in early clinical development, generating the pharmacokinetic, pharmacodynamic and translational insights needed to optimize drug development and support regulatory decision-making. /ppbr / /ppstrongWhat will you do? /strong /ppbr / /pp - Support the implementation of Clinical Pharmacology and Early Clinical Development plans with scientific rigor and a high level of autonomy. /pp - Provide guidance and scientific mentorship to Clinical Pharmacology Scientists and Associate Scientists within the team. /pp - Coordinate and oversee bioanalytical activities, including sample shipment tracking, vendor management, review of validation plans, budgets and work orders. /pp - Perform pharmacokinetic analyses, including Non-Compartmental Analysis (NCA), Population Pharmacokinetic (PopPK) analysis and Physiologically Based Pharmacokinetic (PBPK) modeling. /pp - Conduct pharmacodynamic and PK/PD analyses to assess treatment efficacy, dose-limiting toxicities and exposure-response relationships. /pp - Support first-in-human (FIH) studies, including ECG/Holter monitoring activities and c-QT/t-QT analyses.



/pp - Contribute to Model-Informed Drug Development (MIDD) initiatives through pharmacometric analyses, simulations and interpretation of results. /pp - Develop and maintain high-quality analytical workflows and databases following Good Coding Practices. /pp - Contribute to Clinical Pharmacology sections of study protocols, development plans, scientific publications and technical reports. /pp - Provide scientific support to Regulatory Affairs activities and interactions with agencies such as the EMA and FDA. /pp - Collaborate closely with cross-functional teams including Medical Oncology, Biostatistics, Data Management and other key stakeholders. /pp - Participate in departmental initiatives that contribute to the overall success of Early Clinical Development programs. /ppbr / /ppstrongPosition requirements /strong /ppbr / /pp - Bachelor’s degree in strongPharmacy, Medicine, Biology, Biotechnology /strong or a related scientific discipline. /pp - Master’s degree and PhD in strongPharmacology /strong, Immunology, Computational Biology, Bioinformatics, Biostatistics or a related field. /pp - Fluent English, both written and spoken. /pp - More than 3 years of experience in clinical research, preferably within pharmacology, immunology or translational medicine. /pp - Experience authoring scientific publications and technical reports.



/pp - Proven expertise in pharmacometric modeling tools such as strongNONMEM, Monolix, PK-Sim or similar platforms. /strong /pp - Strong programming skills in R and SAS for data analysis and process automation. /pp - Knowledge of additional programming languages such as Python and Bash. /pp - Experience in bioanalysis and biomarker evaluation. /pp - Solid understanding of statistical methodologies, including descriptive, univariate and multivariate analyses. /pp - Experience withstrong Next-Generation Sequencing /strong(NGS), pharmacogenetics, genotyping analyses and bioinformatics pipelines. /pp - Excellent communication skills and the ability to work independently while contributing effectively within multidisciplinary teams. /ppbr / /ppstrongWhat do we offer? /strong /ppbr / /pp - Competitive annual salary and performance-based bonus. /pp - Comprehensive benefits package, including private health insurance, employee share plan, company canteen, continuous training and development opportunities, among others. /pp - Versátil start time (7:30h to 9:30h) and intensive working hours on Fridays. /pp - Hybrid working model available after successfully completing the six-month probation period, combining on-site collaboration with remote work flexibility. /pp - The opportunity to contribute to groundbreaking oncology research in an innovative and science-driven environment. xhfqzwm /pp - A strong commitment to diversity, equal opportunities and an inclusive work environment where all talent is valued and respected. /ppbr / /ppstrongIf you are passionate about clinical pharmacology, translational science and innovative drug development, we would love to hear from you. /strong /p

📌 Clinical Pharmacology Principal Scientist (Madrid)
🏢 BUSINESS SOLUTIONS by TakeTalent
📍 Madrid